node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CA_C0212 | folA/folK | CA_C0212 | CA_C2927 | Biotin-(acetyl-CoA carboxylase) ligase. | Dihydroneopterin aldolase/7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase fusion protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.746 |
CA_C0212 | nadA | CA_C0212 | CA_C1025 | Biotin-(acetyl-CoA carboxylase) ligase. | Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.630 |
CA_C0212 | nadB | CA_C0212 | CA_C1024 | Biotin-(acetyl-CoA carboxylase) ligase. | Aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.616 |
CA_C0212 | nadC | CA_C0212 | CA_C1023 | Biotin-(acetyl-CoA carboxylase) ligase. | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.597 |
CA_C0212 | nadD | CA_C0212 | CA_C1262 | Biotin-(acetyl-CoA carboxylase) ligase. | Predicted nucleotidyltransferases of NarD/TagD family (N-term. domain), yqeJ ortholog; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.517 |
CA_C0212 | nadE | CA_C0212 | CA_C1050 | Biotin-(acetyl-CoA carboxylase) ligase. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.712 |
CA_C0212 | nadE-2 | CA_C0212 | CA_C1782 | Biotin-(acetyl-CoA carboxylase) ligase. | NH(3)-dependent NAD(+) synthase (nadE) fused to amidohydrolase domain; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.712 |
CA_C0212 | ribD | CA_C0212 | CA_C0590 | Biotin-(acetyl-CoA carboxylase) ligase. | Riboflavin biosynthesis protein RIBD (pirimidine deaminase and pirimidine reductase); Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.634 |
CA_C0212 | vals | CA_C0212 | CA_C2399 | Biotin-(acetyl-CoA carboxylase) ligase. | Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.456 |
cysE | nadA | CA_C0687 | CA_C1025 | Serine acetyltransferase. | Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.894 |
folA/folK | CA_C0212 | CA_C2927 | CA_C0212 | Dihydroneopterin aldolase/7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase fusion protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Biotin-(acetyl-CoA carboxylase) ligase. | 0.746 |
folA/folK | nadA | CA_C2927 | CA_C1025 | Dihydroneopterin aldolase/7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase fusion protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.667 |
folA/folK | nadB | CA_C2927 | CA_C1024 | Dihydroneopterin aldolase/7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase fusion protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.519 |
folA/folK | nadC | CA_C2927 | CA_C1023 | Dihydroneopterin aldolase/7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase fusion protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.641 |
folA/folK | nadD | CA_C2927 | CA_C1262 | Dihydroneopterin aldolase/7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase fusion protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Predicted nucleotidyltransferases of NarD/TagD family (N-term. domain), yqeJ ortholog; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.616 |
folA/folK | nadE | CA_C2927 | CA_C1050 | Dihydroneopterin aldolase/7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase fusion protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.645 |
folA/folK | nadE-2 | CA_C2927 | CA_C1782 | Dihydroneopterin aldolase/7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase fusion protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | NH(3)-dependent NAD(+) synthase (nadE) fused to amidohydrolase domain; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.645 |
folA/folK | ribD | CA_C2927 | CA_C0590 | Dihydroneopterin aldolase/7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase fusion protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Riboflavin biosynthesis protein RIBD (pirimidine deaminase and pirimidine reductase); Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.826 |
nadA | CA_C0212 | CA_C1025 | CA_C0212 | Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | Biotin-(acetyl-CoA carboxylase) ligase. | 0.630 |
nadA | cysE | CA_C1025 | CA_C0687 | Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | Serine acetyltransferase. | 0.894 |