node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CA_C3674 | addA | CA_C3674 | CA_C2262 | Two CBS domain containing protein. | ATP-dependent exonuclease (exonuclease V) synthesis protein AddA (helicase and exonuclease domains); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily. | 0.817 |
addA | CA_C3674 | CA_C2262 | CA_C3674 | ATP-dependent exonuclease (exonuclease V) synthesis protein AddA (helicase and exonuclease domains); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily. | Two CBS domain containing protein. | 0.817 |
addA | addB | CA_C2262 | CA_C2263 | ATP-dependent exonuclease (exonuclease V) synthesis protein AddA (helicase and exonuclease domains); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily. | ATP-dependent exonuclease synthesis protein AddB (superfamily I helicase); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity. | 0.999 |
addA | recD-2 | CA_C2262 | CA_C2854 | ATP-dependent exonuclease (exonuclease V) synthesis protein AddA (helicase and exonuclease domains); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily. | ATP-dependent exoDNAse (exonuclease V), alpha subunit, RecD; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. | 0.926 |
addA | recJ-2 | CA_C2262 | CA_C2232 | ATP-dependent exonuclease (exonuclease V) synthesis protein AddA (helicase and exonuclease domains); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily. | SsDNA Exonuclease, RecJ. | 0.804 |
addA | recO | CA_C2262 | CA_C1309 | ATP-dependent exonuclease (exonuclease V) synthesis protein AddA (helicase and exonuclease domains); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily. | Hypothetical protein; Involved in DNA repair and RecF pathway recombination. | 0.838 |
addA | recQ | CA_C2262 | CA_C2687 | ATP-dependent exonuclease (exonuclease V) synthesis protein AddA (helicase and exonuclease domains); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily. | RecQ protein, superfamily II DNA helicase. | 0.782 |
addA | recX | CA_C2262 | CA_C2410 | ATP-dependent exonuclease (exonuclease V) synthesis protein AddA (helicase and exonuclease domains); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily. | Uncharacterized protein recX; Modulates RecA activity; Belongs to the RecX family. | 0.802 |
addA | ruvA | CA_C2262 | CA_C2285 | ATP-dependent exonuclease (exonuclease V) synthesis protein AddA (helicase and exonuclease domains); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily. | Holliday junction specific DNA helicase, subunit ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.782 |
addA | sbcC | CA_C2262 | CA_C2736 | ATP-dependent exonuclease (exonuclease V) synthesis protein AddA (helicase and exonuclease domains); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily. | ATPase involved in DNA repair; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity); Belongs to the SMC family. SbcC subfamily. | 0.797 |
addA | sbcD | CA_C2262 | CA_C2737 | ATP-dependent exonuclease (exonuclease V) synthesis protein AddA (helicase and exonuclease domains); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily. | DNA repair exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.840 |
addB | addA | CA_C2263 | CA_C2262 | ATP-dependent exonuclease synthesis protein AddB (superfamily I helicase); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity. | ATP-dependent exonuclease (exonuclease V) synthesis protein AddA (helicase and exonuclease domains); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily. | 0.999 |
addB | recD-2 | CA_C2263 | CA_C2854 | ATP-dependent exonuclease synthesis protein AddB (superfamily I helicase); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity. | ATP-dependent exoDNAse (exonuclease V), alpha subunit, RecD; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. | 0.728 |
addB | recJ-2 | CA_C2263 | CA_C2232 | ATP-dependent exonuclease synthesis protein AddB (superfamily I helicase); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity. | SsDNA Exonuclease, RecJ. | 0.776 |
addB | recO | CA_C2263 | CA_C1309 | ATP-dependent exonuclease synthesis protein AddB (superfamily I helicase); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity. | Hypothetical protein; Involved in DNA repair and RecF pathway recombination. | 0.823 |
addB | recQ | CA_C2263 | CA_C2687 | ATP-dependent exonuclease synthesis protein AddB (superfamily I helicase); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity. | RecQ protein, superfamily II DNA helicase. | 0.742 |
addB | recX | CA_C2263 | CA_C2410 | ATP-dependent exonuclease synthesis protein AddB (superfamily I helicase); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity. | Uncharacterized protein recX; Modulates RecA activity; Belongs to the RecX family. | 0.781 |
addB | ruvA | CA_C2263 | CA_C2285 | ATP-dependent exonuclease synthesis protein AddB (superfamily I helicase); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity. | Holliday junction specific DNA helicase, subunit ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.758 |
addB | sbcC | CA_C2263 | CA_C2736 | ATP-dependent exonuclease synthesis protein AddB (superfamily I helicase); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity. | ATPase involved in DNA repair; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity); Belongs to the SMC family. SbcC subfamily. | 0.749 |
addB | sbcD | CA_C2263 | CA_C2737 | ATP-dependent exonuclease synthesis protein AddB (superfamily I helicase); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity. | DNA repair exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.808 |