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hprK hprK lgt lgt PEPE_0609 PEPE_0609 PEPE_0440 PEPE_0440 PEPE_0439 PEPE_0439 PEPE_0142 PEPE_0142 PEPE_1164 PEPE_1164 gpsA gpsA PEPE_0832 PEPE_0832 PEPE_0610 PEPE_0610 PEPE_0444 PEPE_0444
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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hprKHpr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] (312 aa)    
Predicted Functional Partners:
lgt
Prolipoprotein diacylglyceryltransferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
  
  
 0.912
PEPE_0609
Phosphotransferase system, HPr-related protein.
 
 
 
 0.860
PEPE_0440
Predicted membrane protein.
     
 0.813
PEPE_0439
Putative stress-responsive transcriptional regulator.
       0.767
PEPE_0142
Fructose PTS system EIIBC or EIIC component; TC 4.A.2.1.8; TC 4.A.2.1.8; TC 4.A.2.1.8.
  
  
 0.698
PEPE_1164
Fructose PTS system EIIBC or EIIC component; TC 4.A.2.1.4; TC 4.A.2.1.4; TC 4.A.2.1.4.
  
  
 0.698
gpsA
Glycerol 3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.693
PEPE_0832
Serine/threonine protein kinase with beta-lactam (PASTA) domains.
   
 
 0.690
PEPE_0610
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
   
 0.629
PEPE_0444
UDP-glucose pyrophosphorylase.
       0.601
Your Current Organism:
Pediococcus pentosaceus
NCBI taxonomy Id: 278197
Other names: P. pentosaceus ATCC 25745, Pediococcus pentosaceus ATCC 25745, Pediococcus pentosaceus str. ATCC 25745, Pediococcus pentosaceus strain ATCC 25745
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