STRINGSTRING
menD menD menF menF menH menH ABL66104.1 ABL66104.1 menB menB ABL66105.1 ABL66105.1 menA menA ABL65664.1 ABL65664.1 ABL66099.1 ABL66099.1 ABL66098.1 ABL66098.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
menD2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). (587 aa)    
Predicted Functional Partners:
menF
Isochorismate synthases; Catalyzes the conversion of chorismate to isochorismate.
 
 0.999
menH
Alpha/beta hydrolase fold protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
 
 0.998
ABL66104.1
KEGG: plt:Plut_0327 O-succinylbenzoate-CoA synthase.
   
 0.988
menB
1,4-Dihydroxy-2-naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
 
  
 0.928
ABL66105.1
TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: cch:Cag_1672 O-succinylbenzoate-CoA ligase.
 
   
 0.873
menA
1,4-dihydroxy-2-naphtoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
   
 0.846
ABL65664.1
TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: cch:Cag_0930 phenylacetic acid degradation-related protein.
 
   
 0.575
ABL66099.1
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cch:Cag_1702 TPR repeat.
       0.487
ABL66098.1
PFAM: Heavy metal transport/detoxification protein; KEGG: cte:CT1835 heavy-metal-associated domain family protein.
 
     0.430
Your Current Organism:
Chlorobium phaeobacteroides DSM 266
NCBI taxonomy Id: 290317
Other names: C. phaeobacteroides DSM 266, Chlorobium phaeobacteroides DSMZ 266(T), Chlorobium phaeobacteroides str. DSM 266, Chlorobium phaeobacteroides strain DSM 266
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