node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Wbm0369 | glyQ | Wbm0369 | Wbm0370 | Phosphatidylglycerophosphatase A, PgpA. | Glycyl-tRNA synthetase, alpha subunit. | 0.635 |
Wbm0369 | glyS | Wbm0369 | Wbm0371 | Phosphatidylglycerophosphatase A, PgpA. | Glycyl-tRNA synthetase, beta subunit. | 0.635 |
Wbm0369 | uvrC | Wbm0369 | Wbm0372 | Phosphatidylglycerophosphatase A, PgpA. | Nuclease subunit of the excinuclease complex, UvrC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.628 |
Wbm0628 | mutL | Wbm0628 | Wbm0396 | Superfamily I DNA and RNA helicase, UvrD. | DNA mismatch repair enzyme MutL, predicted ATPase; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.891 |
Wbm0628 | mutM | Wbm0628 | Wbm0589 | Superfamily I DNA and RNA helicase, UvrD. | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.436 |
Wbm0628 | polA | Wbm0628 | Wbm0725 | Superfamily I DNA and RNA helicase, UvrD. | DNA polymerase I, PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.784 |
Wbm0628 | uvrA | Wbm0628 | Wbm0263 | Superfamily I DNA and RNA helicase, UvrD. | Excinuclease ATPase subunit, UvrA; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.679 |
Wbm0628 | uvrB | Wbm0628 | Wbm0773 | Superfamily I DNA and RNA helicase, UvrD. | Helicase subunit of the DNA excision repair complex, UvrB; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is foun [...] | 0.925 |
Wbm0628 | uvrC | Wbm0628 | Wbm0372 | Superfamily I DNA and RNA helicase, UvrD. | Nuclease subunit of the excinuclease complex, UvrC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.763 |
glyQ | Wbm0369 | Wbm0370 | Wbm0369 | Glycyl-tRNA synthetase, alpha subunit. | Phosphatidylglycerophosphatase A, PgpA. | 0.635 |
glyQ | glyS | Wbm0370 | Wbm0371 | Glycyl-tRNA synthetase, alpha subunit. | Glycyl-tRNA synthetase, beta subunit. | 0.999 |
glyQ | guaA | Wbm0370 | Wbm0443 | Glycyl-tRNA synthetase, alpha subunit. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.693 |
glyQ | uvrC | Wbm0370 | Wbm0372 | Glycyl-tRNA synthetase, alpha subunit. | Nuclease subunit of the excinuclease complex, UvrC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.773 |
glyS | Wbm0369 | Wbm0371 | Wbm0369 | Glycyl-tRNA synthetase, beta subunit. | Phosphatidylglycerophosphatase A, PgpA. | 0.635 |
glyS | glyQ | Wbm0371 | Wbm0370 | Glycyl-tRNA synthetase, beta subunit. | Glycyl-tRNA synthetase, alpha subunit. | 0.999 |
glyS | guaA | Wbm0371 | Wbm0443 | Glycyl-tRNA synthetase, beta subunit. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.441 |
glyS | uvrC | Wbm0371 | Wbm0372 | Glycyl-tRNA synthetase, beta subunit. | Nuclease subunit of the excinuclease complex, UvrC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.773 |
guaA | glyQ | Wbm0443 | Wbm0370 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Glycyl-tRNA synthetase, alpha subunit. | 0.693 |
guaA | glyS | Wbm0443 | Wbm0371 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Glycyl-tRNA synthetase, beta subunit. | 0.441 |
guaA | mutL | Wbm0443 | Wbm0396 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | DNA mismatch repair enzyme MutL, predicted ATPase; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.477 |