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mtnN mtnN luxS luxS yrrT yrrT BPUM_2361 BPUM_2361 mtnK mtnK speE speE BPUM_2360 BPUM_2360 BPUM_2090 BPUM_2090 bioB bioB BPUM_2080 BPUM_2080 deoD deoD
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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mtnN5'-methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (231 aa)    
Predicted Functional Partners:
luxS
S-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
 
 
 0.974
yrrT
SAM-dependent methyltransferase; Could be a S-adenosyl-L-methionine-dependent methyltransferase.
  
 
 0.916
BPUM_2361
Cysteine synthase.
  
  
 0.914
mtnK
Methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
     
 0.858
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
     
  0.803
BPUM_2360
Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine.
  
 
 0.734
BPUM_2090
ADP-ribose pyrophosphatase.
  
 
 0.700
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
     
 0.690
BPUM_2080
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.687
deoD
Purine nucleoside phosphorylase DeoD-type.
  
 
  0.677
Your Current Organism:
Bacillus pumilus
NCBI taxonomy Id: 315750
Other names: B. pumilus SAFR-032, Bacillus pumilus SAFR-032, Bacillus pumilus str. SAFR-032, Bacillus pumilus strain SAFR-032
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