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ilvC ilvC RPC_3253 RPC_3253 ilvD ilvD RPC_3191 RPC_3191 RPC_4380 RPC_4380 RPC_3255 RPC_3255 ilvD-2 ilvD-2 RPC_1693 RPC_1693 RPC_3648 RPC_3648 RPC_2090 RPC_2090 RPC_3491 RPC_3491
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)    
Predicted Functional Partners:
RPC_3253
Acetolactate synthase, small subunit.
 
 
 0.997
ilvD
Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.995
RPC_3191
Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.995
RPC_4380
Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.995
RPC_3255
Acetolactate synthase, large subunit.
 
 
 0.994
ilvD-2
Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.994
RPC_1693
Acetolactate synthase, large subunit; Belongs to the TPP enzyme family.
 
 
 0.993
RPC_3648
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.991
RPC_2090
Thiamine pyrophosphate enzyme-like TPP-binding.
  
 
 0.976
RPC_3491
Thiamine pyrophosphate enzyme-like TPP-binding.
  
 
 0.976
Your Current Organism:
Rhodopseudomonas palustris BisB18
NCBI taxonomy Id: 316056
Other names: R. palustris BisB18, Rhodopseudomonas palustris str. BisB18, Rhodopseudomonas palustris strain BisB18
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