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trpF trpF trpC trpC trpB trpB trpD trpD trpA trpA trpG trpG trpE trpE CYB_0333 CYB_0333 hisIE hisIE CYB_2299 CYB_2299 CYB_0193 CYB_0193
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
trpFN-(5'phosphoribosyl)anthranilate isomerase; Identified by similarity to SP:Q56320; match to protein family HMM PF00697; Belongs to the TrpF family. (233 aa)    
Predicted Functional Partners:
trpC
Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM PF00218; Belongs to the TrpC family.
 
 0.999
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.998
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.995
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.987
trpG
Anthranilate synthase component II; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566.
 
  
 0.981
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
  
 0.970
CYB_0333
Identified by match to protein family HMM PF02885.
 
  
 0.936
hisIE
Histidine biosynthesis bifunctional protein HisIE; Identified by match to protein family HMM PF01502; match to protein family HMM PF01503; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.696
CYB_2299
Isochorismate synthase; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543.
  
   
 0.670
CYB_0193
Conserved hypothetical protein TIGR00730; Identified by match to protein family HMM PF03641.
       0.611
Your Current Organism:
Synechococcus sp. JA23Ba
NCBI taxonomy Id: 321332
Other names: Cyanobacteria bacterium Yellowstone B-Prime, S. sp. JA-2-3B'a(2-13), Synechococcus sp. JA-2-3B'a(2-13)
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