node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ppro_0013 | Ppro_0157 | Ppro_0013 | Ppro_0157 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gme:Gmet_3550 heat shock protein DnaJ-like. | PFAM: Heat shock protein 70; KEGG: cdi:DIP2120 chaperone protein DnaK. | 0.988 |
Ppro_0013 | Ppro_2145 | Ppro_0013 | Ppro_2145 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gme:Gmet_3550 heat shock protein DnaJ-like. | KEGG: ade:Adeh_2261 molecular chaperone-like. | 0.968 |
Ppro_0013 | clpB | Ppro_0013 | Ppro_1737 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gme:Gmet_3550 heat shock protein DnaJ-like. | ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.848 |
Ppro_0013 | clpP | Ppro_0013 | Ppro_1183 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gme:Gmet_3550 heat shock protein DnaJ-like. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.514 |
Ppro_0013 | dnaK | Ppro_0013 | Ppro_1404 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gme:Gmet_3550 heat shock protein DnaJ-like. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.993 |
Ppro_0013 | groL | Ppro_0013 | Ppro_2802 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gme:Gmet_3550 heat shock protein DnaJ-like. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.857 |
Ppro_0013 | groS | Ppro_0013 | Ppro_2803 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gme:Gmet_3550 heat shock protein DnaJ-like. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.681 |
Ppro_0013 | grpE | Ppro_0013 | Ppro_1405 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gme:Gmet_3550 heat shock protein DnaJ-like. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.962 |
Ppro_0013 | htpG | Ppro_0013 | Ppro_1375 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gme:Gmet_3550 heat shock protein DnaJ-like. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.970 |
Ppro_0157 | Ppro_0013 | Ppro_0157 | Ppro_0013 | PFAM: Heat shock protein 70; KEGG: cdi:DIP2120 chaperone protein DnaK. | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gme:Gmet_3550 heat shock protein DnaJ-like. | 0.988 |
Ppro_0157 | Ppro_2145 | Ppro_0157 | Ppro_2145 | PFAM: Heat shock protein 70; KEGG: cdi:DIP2120 chaperone protein DnaK. | KEGG: ade:Adeh_2261 molecular chaperone-like. | 0.465 |
Ppro_0157 | clpB | Ppro_0157 | Ppro_1737 | PFAM: Heat shock protein 70; KEGG: cdi:DIP2120 chaperone protein DnaK. | ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.968 |
Ppro_0157 | clpP | Ppro_0157 | Ppro_1183 | PFAM: Heat shock protein 70; KEGG: cdi:DIP2120 chaperone protein DnaK. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.737 |
Ppro_0157 | dnaJ | Ppro_0157 | Ppro_1403 | PFAM: Heat shock protein 70; KEGG: cdi:DIP2120 chaperone protein DnaK. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.996 |
Ppro_0157 | dnaK | Ppro_0157 | Ppro_1404 | PFAM: Heat shock protein 70; KEGG: cdi:DIP2120 chaperone protein DnaK. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.929 |
Ppro_0157 | groL | Ppro_0157 | Ppro_2802 | PFAM: Heat shock protein 70; KEGG: cdi:DIP2120 chaperone protein DnaK. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.906 |
Ppro_0157 | groS | Ppro_0157 | Ppro_2803 | PFAM: Heat shock protein 70; KEGG: cdi:DIP2120 chaperone protein DnaK. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.871 |
Ppro_0157 | grpE | Ppro_0157 | Ppro_1405 | PFAM: Heat shock protein 70; KEGG: cdi:DIP2120 chaperone protein DnaK. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.983 |
Ppro_0157 | htpG | Ppro_0157 | Ppro_1375 | PFAM: Heat shock protein 70; KEGG: cdi:DIP2120 chaperone protein DnaK. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.992 |
Ppro_2145 | Ppro_0013 | Ppro_2145 | Ppro_0013 | KEGG: ade:Adeh_2261 molecular chaperone-like. | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gme:Gmet_3550 heat shock protein DnaJ-like. | 0.968 |