node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Hhal_0467 | Hhal_2154 | Hhal_0467 | Hhal_2154 | Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; PFAM: ribulose bisphosphate carboxylase, large chain; KEGG: aeh:Mlg_1168 ribulose-bisphosphate carboxylase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.458 |
Hhal_0467 | mtnA | Hhal_0467 | Hhal_0573 | Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; PFAM: ribulose bisphosphate carboxylase, large chain; KEGG: aeh:Mlg_1168 ribulose-bisphosphate carboxylase. | Translation initiation factor 2B subunit I family (IF-2BI); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.533 |
Hhal_0576 | Hhal_0577 | Hhal_0576 | Hhal_0577 | KEGG: aeh:Mlg_0909 phosphoglycolate phosphatase; TIGRFAM: phosphoglycolate phosphatase; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase. | KEGG: aeh:Mlg_0906 squalene/phytoene synthase. | 0.804 |
Hhal_0576 | Hhal_1048 | Hhal_0576 | Hhal_1048 | KEGG: aeh:Mlg_0909 phosphoglycolate phosphatase; TIGRFAM: phosphoglycolate phosphatase; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase. | PFAM: ribulose-phosphate 3-epimerase; KEGG: aeh:Mlg_2834 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.447 |
Hhal_0576 | mtaD | Hhal_0576 | Hhal_0574 | KEGG: aeh:Mlg_0909 phosphoglycolate phosphatase; TIGRFAM: phosphoglycolate phosphatase; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase. | Amidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.765 |
Hhal_0576 | mtnA | Hhal_0576 | Hhal_0573 | KEGG: aeh:Mlg_0909 phosphoglycolate phosphatase; TIGRFAM: phosphoglycolate phosphatase; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase. | Translation initiation factor 2B subunit I family (IF-2BI); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.590 |
Hhal_0576 | ubiG | Hhal_0576 | Hhal_0575 | KEGG: aeh:Mlg_0909 phosphoglycolate phosphatase; TIGRFAM: phosphoglycolate phosphatase; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.831 |
Hhal_0577 | Hhal_0576 | Hhal_0577 | Hhal_0576 | KEGG: aeh:Mlg_0906 squalene/phytoene synthase. | KEGG: aeh:Mlg_0909 phosphoglycolate phosphatase; TIGRFAM: phosphoglycolate phosphatase; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase. | 0.804 |
Hhal_0577 | mtaD | Hhal_0577 | Hhal_0574 | KEGG: aeh:Mlg_0906 squalene/phytoene synthase. | Amidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.691 |
Hhal_0577 | mtnA | Hhal_0577 | Hhal_0573 | KEGG: aeh:Mlg_0906 squalene/phytoene synthase. | Translation initiation factor 2B subunit I family (IF-2BI); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.498 |
Hhal_0577 | ubiG | Hhal_0577 | Hhal_0575 | KEGG: aeh:Mlg_0906 squalene/phytoene synthase. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.804 |
Hhal_1048 | Hhal_0576 | Hhal_1048 | Hhal_0576 | PFAM: ribulose-phosphate 3-epimerase; KEGG: aeh:Mlg_2834 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | KEGG: aeh:Mlg_0909 phosphoglycolate phosphatase; TIGRFAM: phosphoglycolate phosphatase; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase. | 0.447 |
Hhal_1048 | mtnA | Hhal_1048 | Hhal_0573 | PFAM: ribulose-phosphate 3-epimerase; KEGG: aeh:Mlg_2834 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Translation initiation factor 2B subunit I family (IF-2BI); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.648 |
Hhal_1259 | mtaD | Hhal_1259 | Hhal_0574 | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Amidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.978 |
Hhal_1259 | mtnA | Hhal_1259 | Hhal_0573 | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Translation initiation factor 2B subunit I family (IF-2BI); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.969 |
Hhal_2154 | Hhal_0467 | Hhal_2154 | Hhal_0467 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; PFAM: ribulose bisphosphate carboxylase, large chain; KEGG: aeh:Mlg_1168 ribulose-bisphosphate carboxylase. | 0.458 |
Hhal_2154 | mtnA | Hhal_2154 | Hhal_0573 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Translation initiation factor 2B subunit I family (IF-2BI); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.846 |
Hhal_2154 | speE | Hhal_2154 | Hhal_2411 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.418 |
Hhal_2154 | ubiG | Hhal_2154 | Hhal_0575 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.413 |
mtaD | Hhal_0576 | Hhal_0574 | Hhal_0576 | Amidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | KEGG: aeh:Mlg_0909 phosphoglycolate phosphatase; TIGRFAM: phosphoglycolate phosphatase; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase. | 0.765 |