node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mvan_0002 | Mvan_0730 | Mvan_0002 | Mvan_0730 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: mmc:Mmcs_0567 exodeoxyribonuclease III (xth). | 0.793 |
Mvan_0002 | Mvan_1556 | Mvan_0002 | Mvan_1556 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: mmc:Mmcs_1211 exodeoxyribonuclease III (xth); TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase. | 0.793 |
Mvan_0002 | polA | Mvan_0002 | Mvan_3361 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.997 |
Mvan_0002 | ung | Mvan_0002 | Mvan_2152 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.743 |
Mvan_0730 | Mvan_0002 | Mvan_0730 | Mvan_0002 | TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: mmc:Mmcs_0567 exodeoxyribonuclease III (xth). | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.793 |
Mvan_0730 | Mvan_1556 | Mvan_0730 | Mvan_1556 | TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: mmc:Mmcs_0567 exodeoxyribonuclease III (xth). | KEGG: mmc:Mmcs_1211 exodeoxyribonuclease III (xth); TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase. | 0.928 |
Mvan_0730 | nth | Mvan_0730 | Mvan_5433 | TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: mmc:Mmcs_0567 exodeoxyribonuclease III (xth). | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.726 |
Mvan_0730 | polA | Mvan_0730 | Mvan_3361 | TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: mmc:Mmcs_0567 exodeoxyribonuclease III (xth). | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.797 |
Mvan_0730 | ung | Mvan_0730 | Mvan_2152 | TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: mmc:Mmcs_0567 exodeoxyribonuclease III (xth). | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.718 |
Mvan_1556 | Mvan_0002 | Mvan_1556 | Mvan_0002 | KEGG: mmc:Mmcs_1211 exodeoxyribonuclease III (xth); TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.793 |
Mvan_1556 | Mvan_0730 | Mvan_1556 | Mvan_0730 | KEGG: mmc:Mmcs_1211 exodeoxyribonuclease III (xth); TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase. | TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: mmc:Mmcs_0567 exodeoxyribonuclease III (xth). | 0.928 |
Mvan_1556 | nth | Mvan_1556 | Mvan_5433 | KEGG: mmc:Mmcs_1211 exodeoxyribonuclease III (xth); TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.970 |
Mvan_1556 | polA | Mvan_1556 | Mvan_3361 | KEGG: mmc:Mmcs_1211 exodeoxyribonuclease III (xth); TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.797 |
Mvan_1556 | ung | Mvan_1556 | Mvan_2152 | KEGG: mmc:Mmcs_1211 exodeoxyribonuclease III (xth); TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.718 |
Mvan_2149 | Mvan_2150 | Mvan_2149 | Mvan_2150 | KEGG: mmc:Mmcs_1930 putative conserved secreted protein. | PFAM: regulatory protein, AsnC/Lrp family; KEGG: mmc:Mmcs_1931 putative transcriptional regulator, AsnC family. | 0.855 |
Mvan_2149 | thiL | Mvan_2149 | Mvan_2151 | KEGG: mmc:Mmcs_1930 putative conserved secreted protein. | Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.658 |
Mvan_2149 | ung | Mvan_2149 | Mvan_2152 | KEGG: mmc:Mmcs_1930 putative conserved secreted protein. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.613 |
Mvan_2150 | Mvan_2149 | Mvan_2150 | Mvan_2149 | PFAM: regulatory protein, AsnC/Lrp family; KEGG: mmc:Mmcs_1931 putative transcriptional regulator, AsnC family. | KEGG: mmc:Mmcs_1930 putative conserved secreted protein. | 0.855 |
Mvan_2150 | thiL | Mvan_2150 | Mvan_2151 | PFAM: regulatory protein, AsnC/Lrp family; KEGG: mmc:Mmcs_1931 putative transcriptional regulator, AsnC family. | Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.641 |
Mvan_2150 | ung | Mvan_2150 | Mvan_2152 | PFAM: regulatory protein, AsnC/Lrp family; KEGG: mmc:Mmcs_1931 putative transcriptional regulator, AsnC family. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.531 |