STRINGSTRING
pyrB pyrB carA carA pyrC2 pyrC2 carB carB EAT99236.1 EAT99236.1 pyrD pyrD EAT97373.1 EAT97373.1 EAT99203.1 EAT99203.1 EAT99383.1 EAT99383.1 pyrF pyrF purA purA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrBAspartate carbamoyltransferase, catalytic subunit; Pfam matches to PF02729.16 OTCace_N, and to PF00185.19 OTCace; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (309 aa)    
Predicted Functional Partners:
carA
Carbamoylphosphate synthase, small subunit; Pfam matches to PF00988.17 CPSase_sm_chain, and to PF00117.23 GATase, and to PF07722.8 Peptidase_C26; Belongs to the CarA family.
 
 0.999
pyrC2
Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 0.999
carB
Carbamoylphosphate synthase, large subunit; Pfam matches to PF02786.12 CPSase_L_D2, and to PF02787.14 CPSase_L_D3, and to PF02786.12 CPSase_L_D2, and to PF02142.17 MGS, and to PF00289.17 CPSase_L_chain, and to PF00289.17 CPSase_L_chain, and to PF13535.1 ATP-grasp_4, and to PF13535.1 ATP-grasp_4, and to PF02655.9 ATP-grasp_3, and to PF02222.17 ATP-grasp, and to PF07478.8 Dala_Dala_lig_C; Belongs to the CarB family.
 
 0.999
EAT99236.1
Carbamoyl phosphate synthase-like protein; Pfam matches to PF13535.1 ATP-grasp_4, and to PF02655.9 ATP-grasp_3.
  
 
 0.980
pyrD
Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
  
 0.947
EAT97373.1
Isoaspartyl dipeptidase; Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
  
 
 0.947
EAT99203.1
Isoaspartyl dipeptidase; Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
  
 
 0.947
EAT99383.1
Pfam match to PF00860.15 Xan_ur_permease.
 
  
 0.946
pyrF
Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
 
  
 0.943
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.939
Your Current Organism:
Campylobacter concisus
NCBI taxonomy Id: 360104
Other names: C. concisus 13826, Campylobacter concisus 13826, Campylobacter concisus str. 13826, Campylobacter concisus strain 13826
Server load: low (24%) [HD]