node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACQ69338.1 | lexA | EAT1b_0406 | EAT1b_0408 | PFAM: Resolvase domain; KEGG: bsu:BSU17870 hypothetical protein. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.622 |
ACQ69338.1 | recA | EAT1b_0406 | EAT1b_0429 | PFAM: Resolvase domain; KEGG: bsu:BSU17870 hypothetical protein. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.444 |
ACQ69341.1 | lexA | EAT1b_0409 | EAT1b_0408 | KEGG: bcz:BCZK4926 hypothetical protein. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.779 |
ACQ69447.1 | dinG | EAT1b_0515 | EAT1b_3018 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease. | 0.535 |
ACQ69447.1 | lexA | EAT1b_0515 | EAT1b_0408 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.579 |
ACQ69447.1 | recA | EAT1b_0515 | EAT1b_0429 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.746 |
ACQ69447.1 | uvrC | EAT1b_0515 | EAT1b_2624 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.427 |
ACQ69758.1 | dinG | EAT1b_0828 | EAT1b_3018 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: bsu:BSU21500 UV-damage repair protein. | DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease. | 0.567 |
ACQ69758.1 | lexA | EAT1b_0828 | EAT1b_0408 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: bsu:BSU21500 UV-damage repair protein. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.704 |
ACQ69758.1 | recA | EAT1b_0828 | EAT1b_0429 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: bsu:BSU21500 UV-damage repair protein. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.674 |
ACQ69758.1 | uvrB | EAT1b_0828 | EAT1b_0885 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: bsu:BSU21500 UV-damage repair protein. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.435 |
dinB | dinG | EAT1b_2448 | EAT1b_3018 | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease. | 0.567 |
dinB | lexA | EAT1b_2448 | EAT1b_0408 | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.631 |
dinB | recA | EAT1b_2448 | EAT1b_0429 | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.620 |
dinG | ACQ69447.1 | EAT1b_3018 | EAT1b_0515 | DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.535 |
dinG | ACQ69758.1 | EAT1b_3018 | EAT1b_0828 | DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease. | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: bsu:BSU21500 UV-damage repair protein. | 0.567 |
dinG | dinB | EAT1b_3018 | EAT1b_2448 | DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease. | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.567 |
dinG | lexA | EAT1b_3018 | EAT1b_0408 | DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.613 |
dinG | recA | EAT1b_3018 | EAT1b_0429 | DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.672 |
dinG | uvrB | EAT1b_3018 | EAT1b_0885 | DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.424 |