node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tpen_0559 | Tpen_0562 | Tpen_0559 | Tpen_0562 | Hypothetical protein. | PFAM: histidine triad (HIT) protein; KEGG: tko:TK0868 probable bis(5'-adenosyl)-triphosphatase, HIT family. | 0.508 |
Tpen_0559 | fau-1 | Tpen_0559 | Tpen_0561 | Hypothetical protein. | Protein of unknown function DUF402; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. | 0.518 |
Tpen_0559 | rnp4 | Tpen_0559 | Tpen_0560 | Hypothetical protein. | RNAse P, Rpr2/Rpp21 subunit; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. | 0.518 |
Tpen_0562 | Tpen_0559 | Tpen_0562 | Tpen_0559 | PFAM: histidine triad (HIT) protein; KEGG: tko:TK0868 probable bis(5'-adenosyl)-triphosphatase, HIT family. | Hypothetical protein. | 0.508 |
Tpen_0562 | fau-1 | Tpen_0562 | Tpen_0561 | PFAM: histidine triad (HIT) protein; KEGG: tko:TK0868 probable bis(5'-adenosyl)-triphosphatase, HIT family. | Protein of unknown function DUF402; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. | 0.757 |
Tpen_0562 | flpA | Tpen_0562 | Tpen_0377 | PFAM: histidine triad (HIT) protein; KEGG: tko:TK0868 probable bis(5'-adenosyl)-triphosphatase, HIT family. | rRNA 2'-O-methyltransferase fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.547 |
Tpen_0562 | rnp4 | Tpen_0562 | Tpen_0560 | PFAM: histidine triad (HIT) protein; KEGG: tko:TK0868 probable bis(5'-adenosyl)-triphosphatase, HIT family. | RNAse P, Rpr2/Rpp21 subunit; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. | 0.763 |
eif1a | fau-1 | Tpen_0424 | Tpen_0561 | Translation initiation factor 1A (aeIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | Protein of unknown function DUF402; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. | 0.404 |
eif1a | flpA | Tpen_0424 | Tpen_0377 | Translation initiation factor 1A (aeIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | rRNA 2'-O-methyltransferase fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.773 |
eno | fau-1 | Tpen_0112 | Tpen_0561 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Protein of unknown function DUF402; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. | 0.733 |
eno | flpA | Tpen_0112 | Tpen_0377 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | rRNA 2'-O-methyltransferase fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.763 |
fau-1 | Tpen_0559 | Tpen_0561 | Tpen_0559 | Protein of unknown function DUF402; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. | Hypothetical protein. | 0.518 |
fau-1 | Tpen_0562 | Tpen_0561 | Tpen_0562 | Protein of unknown function DUF402; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. | PFAM: histidine triad (HIT) protein; KEGG: tko:TK0868 probable bis(5'-adenosyl)-triphosphatase, HIT family. | 0.757 |
fau-1 | eif1a | Tpen_0561 | Tpen_0424 | Protein of unknown function DUF402; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. | Translation initiation factor 1A (aeIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | 0.404 |
fau-1 | eno | Tpen_0561 | Tpen_0112 | Protein of unknown function DUF402; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.733 |
fau-1 | flpA | Tpen_0561 | Tpen_0377 | Protein of unknown function DUF402; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. | rRNA 2'-O-methyltransferase fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.733 |
fau-1 | moaA | Tpen_0561 | Tpen_0597 | Protein of unknown function DUF402; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. | Putative molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | 0.411 |
fau-1 | rnp4 | Tpen_0561 | Tpen_0560 | Protein of unknown function DUF402; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. | RNAse P, Rpr2/Rpp21 subunit; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. | 0.773 |
flpA | Tpen_0562 | Tpen_0377 | Tpen_0562 | rRNA 2'-O-methyltransferase fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | PFAM: histidine triad (HIT) protein; KEGG: tko:TK0868 probable bis(5'-adenosyl)-triphosphatase, HIT family. | 0.547 |
flpA | eif1a | Tpen_0377 | Tpen_0424 | rRNA 2'-O-methyltransferase fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | Translation initiation factor 1A (aeIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. | 0.773 |