node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHA_0739 | ftsZ | AHA_0739 | AHA_3880 | Putative amidase; Identified by match to protein family HMM PF01425. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.620 |
AHA_0739 | minC | AHA_0739 | AHA_2134 | Putative amidase; Identified by match to protein family HMM PF01425. | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.495 |
AHA_0739 | mreC | AHA_0739 | AHA_0401 | Putative amidase; Identified by match to protein family HMM PF01425. | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. | 0.466 |
AHA_2135 | AHA_2136 | AHA_2135 | AHA_2136 | Conserved hypothetical protein; Identified by match to protein family HMM PF05166. | Membrane-bound lytic murein transglycosylase B; Identified by match to protein family HMM TIGR02283. | 0.785 |
AHA_2135 | minC | AHA_2135 | AHA_2134 | Conserved hypothetical protein; Identified by match to protein family HMM PF05166. | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.642 |
AHA_2135 | minD | AHA_2135 | AHA_2133 | Conserved hypothetical protein; Identified by match to protein family HMM PF05166. | Septum site-determining protein MinD; Identified by match to protein family HMM PF01656; match to protein family HMM TIGR01968. | 0.569 |
AHA_2135 | minE | AHA_2135 | AHA_2132 | Conserved hypothetical protein; Identified by match to protein family HMM PF05166. | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.595 |
AHA_2136 | AHA_2135 | AHA_2136 | AHA_2135 | Membrane-bound lytic murein transglycosylase B; Identified by match to protein family HMM TIGR02283. | Conserved hypothetical protein; Identified by match to protein family HMM PF05166. | 0.785 |
AHA_2136 | minC | AHA_2136 | AHA_2134 | Membrane-bound lytic murein transglycosylase B; Identified by match to protein family HMM TIGR02283. | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.565 |
AHA_2136 | minD | AHA_2136 | AHA_2133 | Membrane-bound lytic murein transglycosylase B; Identified by match to protein family HMM TIGR02283. | Septum site-determining protein MinD; Identified by match to protein family HMM PF01656; match to protein family HMM TIGR01968. | 0.537 |
AHA_2136 | minE | AHA_2136 | AHA_2132 | Membrane-bound lytic murein transglycosylase B; Identified by match to protein family HMM TIGR02283. | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.537 |
ffh | ftsZ | AHA_0665 | AHA_3880 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.578 |
ffh | minC | AHA_0665 | AHA_2134 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.581 |
ftsZ | AHA_0739 | AHA_3880 | AHA_0739 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Putative amidase; Identified by match to protein family HMM PF01425. | 0.620 |
ftsZ | ffh | AHA_3880 | AHA_0665 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | 0.578 |
ftsZ | minC | AHA_3880 | AHA_2134 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.859 |
ftsZ | mreB | AHA_3880 | AHA_0400 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Rod shape-determining protein MreB; Identified by match to protein family HMM PF06723; match to protein family HMM TIGR00904. | 0.921 |
ftsZ | mreC | AHA_3880 | AHA_0401 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. | 0.633 |
minC | AHA_0739 | AHA_2134 | AHA_0739 | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Putative amidase; Identified by match to protein family HMM PF01425. | 0.495 |
minC | AHA_2135 | AHA_2134 | AHA_2135 | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Conserved hypothetical protein; Identified by match to protein family HMM PF05166. | 0.642 |