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csrA csrA fliW fliW Fnod_1509 Fnod_1509 smpB smpB gatC gatC hfq hfq Fnod_0821 Fnod_0821 deoC deoC Fnod_1650 Fnod_1650 Fnod_1531 Fnod_1531 Fnod_0834 Fnod_0834
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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csrACarbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (83 aa)    
Predicted Functional Partners:
fliW
Protein of unknown function DUF180; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
 
 0.996
Fnod_1509
PFAM: protein of unknown function UPF0102; KEGG: tpt:Tpet_0671 protein of unknown function UPF0102; Belongs to the UPF0102 family.
 
     0.815
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
     
 0.809
gatC
glutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.
       0.791
hfq
RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
   
  
 0.717
Fnod_0821
PFAM: flagellar protein FliS; KEGG: tpt:Tpet_1574 flagellar protein FliS.
 
  
 0.680
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
       0.658
Fnod_1650
TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: tma:TM0082 flagellar hook-associated protein 3.
 
  
 0.658
Fnod_1531
CheC, inhibitor of MCP methylation; TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; KEGG: tpt:Tpet_0251 CheC, inhibitor of MCP methylation.
  
   0.656
Fnod_0834
Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
  
  
 0.635
Your Current Organism:
Fervidobacterium nodosum
NCBI taxonomy Id: 381764
Other names: F. nodosum Rt17-B1, Fervidobacterium nodosum Rt17-B1, Fervidobacterium nodosum str. Rt17-B1, Fervidobacterium nodosum strain Rt17-B1
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