node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aave_0140 | queC | Aave_0140 | Aave_0139 | KEGG: rfr:Rfer_0345 hypothetical protein. | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.551 |
Aave_1307 | mnmA | Aave_1307 | Aave_4724 | TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: rfr:Rfer_3301 4Fe-4S cluster binding. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.408 |
Aave_1307 | queA | Aave_1307 | Aave_0590 | TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: rfr:Rfer_3301 4Fe-4S cluster binding. | Queuosine biosynthesis protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.774 |
Aave_1307 | queC | Aave_1307 | Aave_0139 | TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: rfr:Rfer_3301 4Fe-4S cluster binding. | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.407 |
Aave_1307 | queF | Aave_1307 | Aave_1170 | TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: rfr:Rfer_3301 4Fe-4S cluster binding. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.488 |
Aave_3631 | Aave_3845 | Aave_3631 | Aave_3845 | PFAM: GTP cyclohydrolase I; KEGG: pol:Bpro_0869 GTP cyclohydrolase I. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: pol:Bpro_1495 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | 0.991 |
Aave_3631 | queA | Aave_3631 | Aave_0590 | PFAM: GTP cyclohydrolase I; KEGG: pol:Bpro_0869 GTP cyclohydrolase I. | Queuosine biosynthesis protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.467 |
Aave_3631 | queC | Aave_3631 | Aave_0139 | PFAM: GTP cyclohydrolase I; KEGG: pol:Bpro_0869 GTP cyclohydrolase I. | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.482 |
Aave_3631 | queE | Aave_3631 | Aave_3844 | PFAM: GTP cyclohydrolase I; KEGG: pol:Bpro_0869 GTP cyclohydrolase I. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.583 |
Aave_3631 | queF | Aave_3631 | Aave_1170 | PFAM: GTP cyclohydrolase I; KEGG: pol:Bpro_0869 GTP cyclohydrolase I. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.487 |
Aave_3845 | Aave_3631 | Aave_3845 | Aave_3631 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: pol:Bpro_1495 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | PFAM: GTP cyclohydrolase I; KEGG: pol:Bpro_0869 GTP cyclohydrolase I. | 0.991 |
Aave_3845 | queC | Aave_3845 | Aave_0139 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: pol:Bpro_1495 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.951 |
Aave_3845 | queE | Aave_3845 | Aave_3844 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: pol:Bpro_1495 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.998 |
Aave_3845 | queF | Aave_3845 | Aave_1170 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: pol:Bpro_1495 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.865 |
mnmA | Aave_1307 | Aave_4724 | Aave_1307 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: rfr:Rfer_3301 4Fe-4S cluster binding. | 0.408 |
mnmA | queA | Aave_4724 | Aave_0590 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | Queuosine biosynthesis protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.456 |
mnmA | queC | Aave_4724 | Aave_0139 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.404 |
pckG | queC | Aave_0138 | Aave_0139 | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.434 |
queA | Aave_1307 | Aave_0590 | Aave_1307 | Queuosine biosynthesis protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: rfr:Rfer_3301 4Fe-4S cluster binding. | 0.774 |
queA | Aave_3631 | Aave_0590 | Aave_3631 | Queuosine biosynthesis protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | PFAM: GTP cyclohydrolase I; KEGG: pol:Bpro_0869 GTP cyclohydrolase I. | 0.467 |