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bioB bioB bioD bioD Aave_4629 Aave_4629 Aave_3841 Aave_3841 bioF bioF Aave_3214 Aave_3214 Aave_2181 Aave_2181 Aave_3717 Aave_3717 Aave_4744 Aave_4744 thiC thiC Aave_3908 Aave_3908
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (354 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.998
Aave_4629
TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase; KEGG: pol:Bpro_4716 biotin--acetyl-CoA-carboxylase ligase.
  
 
 0.939
Aave_3841
Aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: pol:Bpro_0900 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.918
bioF
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
  
 0.917
Aave_3214
PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: bbr:BB1545 putative biotin sulfoxide reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
     
  0.900
Aave_2181
PFAM: aminotransferase class-III; KEGG: pol:Bpro_0052 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.727
Aave_3717
PFAM: aminotransferase class-III; KEGG: psp:PSPPH_A0108 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.708
Aave_4744
PFAM: aminotransferase class-III; KEGG: pol:Bpro_4286 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.648
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.626
Aave_3908
KEGG: pol:Bpro_1243 biotin synthesis protein BioC.
  
  
 0.550
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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