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pyrB pyrB Rpic_0621 Rpic_0621 Rpic_0623 Rpic_0623 carB carB carA carA Rpic_4022 Rpic_4022 pyrC pyrC pyrD pyrD pyrE pyrE pyrF pyrF purA purA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
pyrBTIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: rso:RSc0678 aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (323 aa)    
Predicted Functional Partners:
Rpic_0621
PFAM: phosphoribosyltransferase; KEGG: rso:RSc0677 pyrimidine regulatory protein PyrR.
 
 0.999
Rpic_0623
TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: rso:RSc0679 dihydroorotase.
 0.999
carB
TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: rso:RSc1521 carbamoyl phosphate synthase large subunit; Belongs to the CarB family.
 
 0.999
carA
TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: rso:RSc1519 carbamoyl phosphate synthase small subunit; Belongs to the CarA family.
 
 0.999
Rpic_4022
Dihydropyrimidinase; KEGG: reh:H16_A0068 D-hydantoinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase; Amidohydrolase 3.
 
 0.994
pyrC
Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
  
 
 0.984
pyrD
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
  
 0.976
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.973
pyrF
TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: rso:RSc2773 orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
  
 0.973
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 
 0.955
Your Current Organism:
Ralstonia pickettii 12J
NCBI taxonomy Id: 402626
Other names: R. pickettii 12J, Ralstonia pickettii str. 12J, Ralstonia pickettii strain 12J
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