STRINGSTRING
nadD nadD rsfS rsfS nadE nadE nadK nadK Plav_2952 Plav_2952 Plav_0732 Plav_0732 Plav_3134 Plav_3134 Plav_1417 Plav_1417 Plav_0254 Plav_0254 Plav_2058 Plav_2058 Plav_2059 Plav_2059
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (201 aa)    
Predicted Functional Partners:
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
 0.975
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.956
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.948
Plav_2952
PFAM: Silent information regulator protein Sir2; KEGG: bbt:BBta_4037 putative transciptional regulatory Sir2-family protein.
   
 0.943
Plav_0732
TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; KEGG: gbe:GbCGDNIH1_0642 nicotinate-nucleotide pyrophosphorylase (carboxylating); Belongs to the NadC/ModD family.
    
 0.940
Plav_3134
PFAM: CinA domain protein; KEGG: hne:HNE_2017 CinA domain protein; Belongs to the CinA family.
  
 
 0.934
Plav_1417
PFAM: CinA domain protein; KEGG: hypothetical protein; Belongs to the CinA family.
  
 
 0.932
Plav_0254
PFAM: NUDIX hydrolase; NADH pyrophosphatase-like; Zinc ribbon NADH pyrophosphatase; KEGG: MutT/NUDIX family protein.
     
 0.904
Plav_2058
NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: nwi:Nwi_0995 alanine dehydrogenase/PNT.
     
 0.904
Plav_2059
KEGG: rpc:RPC_3967 NAD(P) transhydrogenase subunit alpha part.
     
 0.904
Your Current Organism:
Parvibaculum lavamentivorans
NCBI taxonomy Id: 402881
Other names: P. lavamentivorans DS-1, Parvibaculum lavamentivorans DS-1, Parvibaculum lavamentivorans str. DS-1, Parvibaculum lavamentivorans strain DS-1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.