STRINGSTRING
surE surE apt apt guaA guaA guaB guaB pyrR pyrR cmk cmk ABS25356.1 ABS25356.1 pyrH pyrH purH purH ABS28031.1 ABS28031.1 ABS24875.1 ABS24875.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
surEStationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (254 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.966
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
    
 0.946
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.941
pyrR
Phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
  
  
 0.930
cmk
TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: ade:Adeh_1515 cytidylate kinase.
    
 0.928
ABS25356.1
TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: ade:Adeh_1109 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
    
 0.927
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
     
 0.925
purH
TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG: ade:Adeh_2468 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.
     
 0.925
ABS28031.1
PFAM: cyclic nucleotide-binding; phosphoribulokinase/uridine kinase; KEGG: ade:Adeh_3723 cyclic nucleotide-binding domain (cNMP-BD) protein.
  
  
 0.925
ABS24875.1
TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; KEGG: ade:Adeh_0617 glycosyl transferase, family 3.
    
 0.924
Your Current Organism:
Anaeromyxobacter sp. Fw1095
NCBI taxonomy Id: 404589
Other names: A. sp. Fw109-5, Anaeromyxobacter sp. Fw109-5
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