node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABS24222.1 | dut | Anae109_0002 | Anae109_1147 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.848 |
ABS25356.1 | ABS27585.1 | Anae109_1148 | Anae109_3401 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: ade:Adeh_1109 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: mxa:MXAN_5140 hypothetical protein. | 0.921 |
ABS25356.1 | dut | Anae109_1148 | Anae109_1147 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: ade:Adeh_1109 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.805 |
ABS25356.1 | ndk | Anae109_1148 | Anae109_2182 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: ade:Adeh_1109 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.416 |
ABS25356.1 | surE | Anae109_1148 | Anae109_0790 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: ade:Adeh_1109 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.927 |
ABS25702.1 | dut | Anae109_1495 | Anae109_1147 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.931 |
ABS26463.1 | ABS27585.1 | Anae109_2261 | Anae109_3401 | PFAM: CMP/dCMP deaminase zinc-binding; KEGG: ade:Adeh_1552 zinc-binding CMP/dCMP deaminase. | KEGG: mxa:MXAN_5140 hypothetical protein. | 0.906 |
ABS26463.1 | dut | Anae109_2261 | Anae109_1147 | PFAM: CMP/dCMP deaminase zinc-binding; KEGG: ade:Adeh_1552 zinc-binding CMP/dCMP deaminase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.942 |
ABS26463.1 | surE | Anae109_2261 | Anae109_0790 | PFAM: CMP/dCMP deaminase zinc-binding; KEGG: ade:Adeh_1552 zinc-binding CMP/dCMP deaminase. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
ABS26463.1 | thyX | Anae109_2261 | Anae109_1187 | PFAM: CMP/dCMP deaminase zinc-binding; KEGG: ade:Adeh_1552 zinc-binding CMP/dCMP deaminase. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.910 |
ABS26463.1 | tmk | Anae109_2261 | Anae109_2080 | PFAM: CMP/dCMP deaminase zinc-binding; KEGG: ade:Adeh_1552 zinc-binding CMP/dCMP deaminase. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.922 |
ABS26463.1 | tmk-2 | Anae109_2261 | Anae109_3375 | PFAM: CMP/dCMP deaminase zinc-binding; KEGG: ade:Adeh_1552 zinc-binding CMP/dCMP deaminase. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.922 |
ABS27585.1 | ABS25356.1 | Anae109_3401 | Anae109_1148 | KEGG: mxa:MXAN_5140 hypothetical protein. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: ade:Adeh_1109 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.921 |
ABS27585.1 | ABS26463.1 | Anae109_3401 | Anae109_2261 | KEGG: mxa:MXAN_5140 hypothetical protein. | PFAM: CMP/dCMP deaminase zinc-binding; KEGG: ade:Adeh_1552 zinc-binding CMP/dCMP deaminase. | 0.906 |
ABS27585.1 | dut | Anae109_3401 | Anae109_1147 | KEGG: mxa:MXAN_5140 hypothetical protein. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.900 |
ABS27585.1 | surE | Anae109_3401 | Anae109_0790 | KEGG: mxa:MXAN_5140 hypothetical protein. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.919 |
ABS27585.1 | thyX | Anae109_3401 | Anae109_1187 | KEGG: mxa:MXAN_5140 hypothetical protein. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.900 |
ABS27585.1 | tmk | Anae109_3401 | Anae109_2080 | KEGG: mxa:MXAN_5140 hypothetical protein. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.915 |
ABS27585.1 | tmk-2 | Anae109_3401 | Anae109_3375 | KEGG: mxa:MXAN_5140 hypothetical protein. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.915 |
dut | ABS24222.1 | Anae109_1147 | Anae109_0002 | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.848 |