STRINGSTRING
tfe tfe tfb tfb tbp tbp rpoH rpoH ABR65635.1 ABR65635.1 ABR65640.1 ABR65640.1 rpoN rpoN ABR66313.1 ABR66313.1 ABR65741.1 ABR65741.1 ABR65673.1 ABR65673.1 ABR65674.1 ABR65674.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tfeTranscription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongatio [...] (185 aa)    
Predicted Functional Partners:
tfb
Transcription factor TFIIB cyclin-related; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
  
 
 0.998
tbp
TATA-box binding; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
  
 0.992
rpoH
RNA polymerase Rpb5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
  
 
 0.987
ABR65635.1
PFAM: RNA polymerase dimerisation; RNA polymerase insert; SMART: RNA polymerase RpoA/D/Rpb3-type; KEGG: mmp:MMP1322 DNA-directed RNA polymerase, subunit D.
  
 
 0.985
ABR65640.1
PFAM: RNA polymerase Rpb6; KEGG: mmp:MMP1327 DNA-directed RNA polymerase, subunit K.
  
 
 0.985
rpoN
RNA polymerase, N/8 Kd subunits; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.
  
 
 0.984
ABR66313.1
SMART: RNA polymerase Rbp10; KEGG: mmp:MMP0248 DNA-directed RNA polymerase related protein.
    
 0.982
ABR65741.1
TIGRFAM: transcription factor S; PFAM: Transcription factor TFIIS; DNA-directed RNA polymerase, M/15 kDa subunit; KEGG: mmp:MMP1429 transcription factor TFIIS:DNA-directed RNA polymerase, M/15 kDa subunit; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
  
 
 0.975
ABR65673.1
PFAM: RNA polymerase Rpb2 domain 2; RNA polymerase beta subunit; RNA polymerase Rpb2 domain 3; KEGG: mmp:MMP1361 DNA-directed RNA polymerase subunit B; Belongs to the RNA polymerase beta chain family.
  
 0.965
ABR65674.1
RNA polymerase Rpb2 domain 6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.956
Your Current Organism:
Methanococcus maripaludis C7
NCBI taxonomy Id: 426368
Other names: M. maripaludis C7, Methanococcus maripaludis str. C7, Methanococcus maripaludis strain C7
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.