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ribH ribH ribBA ribBA ACD65822.1 ACD65822.1 ACD66568.1 ACD66568.1 nusB nusB ACD66007.1 ACD66007.1 guaB guaB ACD66887.1 ACD66887.1 ACD65871.1 ACD65871.1 ACD66898.1 ACD66898.1 pyrB pyrB
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. (154 aa)    
Predicted Functional Partners:
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
 
 
 0.999
ACD65822.1
TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: aae:aq_1707 riboflavin synthase alpha chain.
 
 0.998
ACD66568.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
 
 0.986
nusB
NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
  
  
 0.958
ACD66007.1
TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; FAD synthetase; Riboflavin kinase; KEGG: aae:aq_139 riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family.
  
 
 0.919
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.879
ACD66887.1
PFAM: S-adenosylmethionine synthetase; KEGG: aae:aq_1154 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family.
  
 
 0.852
ACD65871.1
KEGG: aae:aq_436 5-amino-6-(5-phosphoribosylamino)uracil reductase; TIGRFAM: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase; PFAM: bifunctional deaminase-reductase domain protein.
 
 
 0.839
ACD66898.1
PFAM: metallophosphoesterase; KEGG: mja:MJ0912 hypothetical protein.
       0.800
pyrB
KEGG: drm:Dred_1681 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
    0.762
Your Current Organism:
Sulfurihydrogenibium sp. YO3AOP1
NCBI taxonomy Id: 436114
Other names: S. sp. YO3AOP1
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