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panC panC panB panB panD panD coaX coaX ACD66021.1 ACD66021.1 cmk cmk ACD65992.1 ACD65992.1 ACD66862.1 ACD66862.1 ACD67122.1 ACD67122.1 ACD67127.1 ACD67127.1 ACD67123.1 ACD67123.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
panCPantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (280 aa)    
Predicted Functional Partners:
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
 0.997
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
 
 0.994
coaX
Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family.
  
 
 0.959
ACD66021.1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.930
cmk
KEGG: tte:TTE1350 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
      0.910
ACD65992.1
PFAM: aminotransferase class-III; KEGG: azc:AZC_1645 aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.900
ACD66862.1
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
  
 
 0.863
ACD67122.1
PFAM: transglutaminase domain protein; KEGG: sat:SYN_00741 transglutaminase-like enzymes, putative cysteine proteases.
       0.793
ACD67127.1
PFAM: Rhomboid family protein; KEGG: aae:aq_1327 hypothetical protein.
  
    0.789
ACD67123.1
PFAM: protein of unknown function DUF58; KEGG: sfu:Sfum_3276 protein of unknown function DUF58.
       0.788
Your Current Organism:
Sulfurihydrogenibium sp. YO3AOP1
NCBI taxonomy Id: 436114
Other names: S. sp. YO3AOP1
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