STRINGSTRING
Elen_1325 Elen_1325 Elen_0198 Elen_0198 Elen_1793 Elen_1793 Elen_1988 Elen_1988 Elen_1986 Elen_1986 Elen_1205 Elen_1205 Elen_1985 Elen_1985 Elen_0027 Elen_0027 accD accD Elen_1202 Elen_1202 Elen_2568 Elen_2568
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Elen_1325Short-chain dehydrogenase/reductase SDR; Involved in the modification of secondary bile acids to form iso-bile acids via epimerization of the 3-OH group through 3-oxo- intermediate. In vitro, catalyzes the reversible oxidation of 12-alpha- hydroxy-3-oxo-5-beta-cholan-24-oate (3-oxo-DCA) and 3-oxo-5-beta- cholan-24-oate (3-oxo-LCA) to yield isodeoxycholate (isoDCA) and isolithocholate (isoLCA), respectively. It prefers NADH to NADPH. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)    
Predicted Functional Partners:
Elen_0198
Short-chain dehydrogenase/reductase SDR; Involved in the modification of secondary bile acids to form iso-bile acids via epimerization of the 3-OH group through 3-oxo- intermediate. In vitro, catalyzes the reversible oxidation of 12-alpha- hydroxy-3-oxo-5-beta-cholan-24-oate (3-oxo-DCA) and 3-oxo-5-beta- cholan-24-oate (3-oxo-LCA) to yield isodeoxycholate (isoDCA) and isolithocholate (isoLCA), respectively. It prefers NADH to NADPH. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 
0.916
Elen_1793
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; KEGG: bsu:BSU38500 D-alanine--D-alanyl carrier protein ligase; Belongs to the ATP-dependent AMP-binding enzyme family.
 
 
 0.760
Elen_1988
TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: spe:Spro_1905 malonyl CoA-acyl carrier protein transacylase.
 
 0.704
Elen_1986
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 0.651
Elen_1205
PFAM: short-chain dehydrogenase/reductase SDR; Male sterility domain; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: mxa:MXAN_0923 oxidoreductase, short chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.620
Elen_1985
PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; thioesterase superfamily protein; KEGG: afw:Anae109_1123 beta-hydroxyacyl-(acyl- carrier-protein) dehydratase FabZ.
 
 
 0.499
Elen_0027
PFAM: metallophosphoesterase; KEGG: scl:sce7166 DNA repair exonuclease family protein.
   
 
 0.488
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
  
 0.485
Elen_1202
PFAM: glycoside hydrolase family 2 sugar binding; glycoside hydrolase family 2 TIM barrel; KEGG: glycosyl hydrolase, family 2; Belongs to the glycosyl hydrolase 2 family.
  
  
 0.457
Elen_2568
KEGG: pla:Plav_0415 hypothetical protein.
  
  
 0.457
Your Current Organism:
Eggerthella lenta
NCBI taxonomy Id: 479437
Other names: E. lenta DSM 2243, Eggerthella lenta DSM 2243, Eggerthella lenta str. DSM 2243, Eggerthella lenta strain DSM 2243
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.