node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CJA_0793 | mrdA-2 | CJA_0793 | CJA_0789 | D-alanyl-D-alanine carboxypeptidase family; Identified by match to protein family HMM PF00768; Belongs to the peptidase S11 family. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.939 |
CJA_0793 | plt103A | CJA_0793 | CJA_0791 | D-alanyl-D-alanine carboxypeptidase family; Identified by match to protein family HMM PF00768; Belongs to the peptidase S11 family. | Peptidoglycan lytic transglycosylase, putative, plt103A; Identified by match to protein family HMM TIGR02282. | 0.662 |
CJA_0793 | rlmH | CJA_0793 | CJA_0788 | D-alanyl-D-alanine carboxypeptidase family; Identified by match to protein family HMM PF00768; Belongs to the peptidase S11 family. | Conserved hypothetical protein TIGR00246; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.604 |
CJA_0793 | rlpA | CJA_0793 | CJA_0792 | D-alanyl-D-alanine carboxypeptidase family; Identified by match to protein family HMM PF00768; Belongs to the peptidase S11 family. | Six5; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.665 |
CJA_0793 | rodA | CJA_0793 | CJA_0790 | D-alanyl-D-alanine carboxypeptidase family; Identified by match to protein family HMM PF00768; Belongs to the peptidase S11 family. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.665 |
CJA_0793 | rsfS | CJA_0793 | CJA_0787 | D-alanyl-D-alanine carboxypeptidase family; Identified by match to protein family HMM PF00768; Belongs to the peptidase S11 family. | Iojap domain protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.406 |
mrdA-2 | CJA_0793 | CJA_0789 | CJA_0793 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | D-alanyl-D-alanine carboxypeptidase family; Identified by match to protein family HMM PF00768; Belongs to the peptidase S11 family. | 0.939 |
mrdA-2 | nadD | CJA_0789 | CJA_0786 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.568 |
mrdA-2 | plt103A | CJA_0789 | CJA_0791 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Peptidoglycan lytic transglycosylase, putative, plt103A; Identified by match to protein family HMM TIGR02282. | 0.866 |
mrdA-2 | proA | CJA_0789 | CJA_0785 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.577 |
mrdA-2 | rlmH | CJA_0789 | CJA_0788 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Conserved hypothetical protein TIGR00246; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.913 |
mrdA-2 | rlpA | CJA_0789 | CJA_0792 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Six5; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.763 |
mrdA-2 | rodA | CJA_0789 | CJA_0790 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.998 |
mrdA-2 | rsfS | CJA_0789 | CJA_0787 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Iojap domain protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.615 |
nadD | mrdA-2 | CJA_0786 | CJA_0789 | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.568 |
nadD | plt103A | CJA_0786 | CJA_0791 | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Peptidoglycan lytic transglycosylase, putative, plt103A; Identified by match to protein family HMM TIGR02282. | 0.489 |
nadD | proA | CJA_0786 | CJA_0785 | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.885 |
nadD | rlmH | CJA_0786 | CJA_0788 | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Conserved hypothetical protein TIGR00246; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.831 |
nadD | rlpA | CJA_0786 | CJA_0792 | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Six5; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.447 |
nadD | rodA | CJA_0786 | CJA_0790 | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.548 |