node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
yafW | yafX | b0246 | b0248 | CP4-6 prophage; Antitoxin component of a type IV toxin-antitoxin (TA) system. Antitoxin that counteracts the effect of cognate toxin YkfI. It does not seem to bind to the cognate toxin but instead induces toxin loss by an unknown mechanism. Co-overexpression of toxin YkfI and antitoxin YafW leads to formation of elongated cells. | CP4-6 prophage; uncharacterized protein; Belongs to the antirestriction protein family. | 0.983 |
yafW | yfjX | b0246 | b2643 | CP4-6 prophage; Antitoxin component of a type IV toxin-antitoxin (TA) system. Antitoxin that counteracts the effect of cognate toxin YkfI. It does not seem to bind to the cognate toxin but instead induces toxin loss by an unknown mechanism. Co-overexpression of toxin YkfI and antitoxin YafW leads to formation of elongated cells. | Uncharacterized protein YfjX; Pseudogene, CP4-57 putative prophage remnant;Phage or Prophage Related; Belongs to the antirestriction protein family. | 0.722 |
yafW | ykfB | b0246 | b0250 | CP4-6 prophage; Antitoxin component of a type IV toxin-antitoxin (TA) system. Antitoxin that counteracts the effect of cognate toxin YkfI. It does not seem to bind to the cognate toxin but instead induces toxin loss by an unknown mechanism. Co-overexpression of toxin YkfI and antitoxin YafW leads to formation of elongated cells. | CP4-6 prophage; uncharacterized protein; To E.coli YfjT. | 0.600 |
yafW | ykfF | b0246 | b0249 | CP4-6 prophage; Antitoxin component of a type IV toxin-antitoxin (TA) system. Antitoxin that counteracts the effect of cognate toxin YkfI. It does not seem to bind to the cognate toxin but instead induces toxin loss by an unknown mechanism. Co-overexpression of toxin YkfI and antitoxin YafW leads to formation of elongated cells. | CP4-6 prophage; uncharacterized protein; Belongs to the UPF0401 family. | 0.844 |
yafW | ykfG | b0246 | b0247 | CP4-6 prophage; Antitoxin component of a type IV toxin-antitoxin (TA) system. Antitoxin that counteracts the effect of cognate toxin YkfI. It does not seem to bind to the cognate toxin but instead induces toxin loss by an unknown mechanism. Co-overexpression of toxin YkfI and antitoxin YafW leads to formation of elongated cells. | CP4-6 prophage; Putative DNA repair protein; Belongs to the UPF0758 family. | 0.943 |
yafW | ykfH | b0246 | b4504 | CP4-6 prophage; Antitoxin component of a type IV toxin-antitoxin (TA) system. Antitoxin that counteracts the effect of cognate toxin YkfI. It does not seem to bind to the cognate toxin but instead induces toxin loss by an unknown mechanism. Co-overexpression of toxin YkfI and antitoxin YafW leads to formation of elongated cells. | Uncharacterized protein; Belongs to the YeeT/YkfH/YpjJ family. | 0.973 |
yafW | ykfI | b0246 | b0245 | CP4-6 prophage; Antitoxin component of a type IV toxin-antitoxin (TA) system. Antitoxin that counteracts the effect of cognate toxin YkfI. It does not seem to bind to the cognate toxin but instead induces toxin loss by an unknown mechanism. Co-overexpression of toxin YkfI and antitoxin YafW leads to formation of elongated cells. | Toxin YkfI; Toxic component of a type IV toxin-antitoxin (TA) system. Acts as a toxin inhibitor that blocks cell division and cell elongation via FtsZ and possibly also MreB (although no interaction with MreB has been proven). Overexpression results in inhibition of growth in liquid cultures and a decrease in colony formation. These effects are overcome by concomitant expression of cognate antitoxin YafW, which leads to toxin loss by an unknown mechanism. Overexpression leads to formation of lemon-shaped cells and cell lysis; inactivated by overexpression of cognate antitoxin YafW but [...] | 0.990 |
yafX | yafW | b0248 | b0246 | CP4-6 prophage; uncharacterized protein; Belongs to the antirestriction protein family. | CP4-6 prophage; Antitoxin component of a type IV toxin-antitoxin (TA) system. Antitoxin that counteracts the effect of cognate toxin YkfI. It does not seem to bind to the cognate toxin but instead induces toxin loss by an unknown mechanism. Co-overexpression of toxin YkfI and antitoxin YafW leads to formation of elongated cells. | 0.983 |
yafX | ykfB | b0248 | b0250 | CP4-6 prophage; uncharacterized protein; Belongs to the antirestriction protein family. | CP4-6 prophage; uncharacterized protein; To E.coli YfjT. | 0.733 |
yafX | ykfF | b0248 | b0249 | CP4-6 prophage; uncharacterized protein; Belongs to the antirestriction protein family. | CP4-6 prophage; uncharacterized protein; Belongs to the UPF0401 family. | 0.963 |
yafX | ykfG | b0248 | b0247 | CP4-6 prophage; uncharacterized protein; Belongs to the antirestriction protein family. | CP4-6 prophage; Putative DNA repair protein; Belongs to the UPF0758 family. | 0.965 |
yafX | ykfH | b0248 | b4504 | CP4-6 prophage; uncharacterized protein; Belongs to the antirestriction protein family. | Uncharacterized protein; Belongs to the YeeT/YkfH/YpjJ family. | 0.978 |
yafX | ykfI | b0248 | b0245 | CP4-6 prophage; uncharacterized protein; Belongs to the antirestriction protein family. | Toxin YkfI; Toxic component of a type IV toxin-antitoxin (TA) system. Acts as a toxin inhibitor that blocks cell division and cell elongation via FtsZ and possibly also MreB (although no interaction with MreB has been proven). Overexpression results in inhibition of growth in liquid cultures and a decrease in colony formation. These effects are overcome by concomitant expression of cognate antitoxin YafW, which leads to toxin loss by an unknown mechanism. Overexpression leads to formation of lemon-shaped cells and cell lysis; inactivated by overexpression of cognate antitoxin YafW but [...] | 0.921 |
yfjX | yafW | b2643 | b0246 | Uncharacterized protein YfjX; Pseudogene, CP4-57 putative prophage remnant;Phage or Prophage Related; Belongs to the antirestriction protein family. | CP4-6 prophage; Antitoxin component of a type IV toxin-antitoxin (TA) system. Antitoxin that counteracts the effect of cognate toxin YkfI. It does not seem to bind to the cognate toxin but instead induces toxin loss by an unknown mechanism. Co-overexpression of toxin YkfI and antitoxin YafW leads to formation of elongated cells. | 0.722 |
yfjX | ykfF | b2643 | b0249 | Uncharacterized protein YfjX; Pseudogene, CP4-57 putative prophage remnant;Phage or Prophage Related; Belongs to the antirestriction protein family. | CP4-6 prophage; uncharacterized protein; Belongs to the UPF0401 family. | 0.535 |
yfjX | ykfH | b2643 | b4504 | Uncharacterized protein YfjX; Pseudogene, CP4-57 putative prophage remnant;Phage or Prophage Related; Belongs to the antirestriction protein family. | Uncharacterized protein; Belongs to the YeeT/YkfH/YpjJ family. | 0.622 |
ykfB | yafW | b0250 | b0246 | CP4-6 prophage; uncharacterized protein; To E.coli YfjT. | CP4-6 prophage; Antitoxin component of a type IV toxin-antitoxin (TA) system. Antitoxin that counteracts the effect of cognate toxin YkfI. It does not seem to bind to the cognate toxin but instead induces toxin loss by an unknown mechanism. Co-overexpression of toxin YkfI and antitoxin YafW leads to formation of elongated cells. | 0.600 |
ykfB | yafX | b0250 | b0248 | CP4-6 prophage; uncharacterized protein; To E.coli YfjT. | CP4-6 prophage; uncharacterized protein; Belongs to the antirestriction protein family. | 0.733 |
ykfB | ykfF | b0250 | b0249 | CP4-6 prophage; uncharacterized protein; To E.coli YfjT. | CP4-6 prophage; uncharacterized protein; Belongs to the UPF0401 family. | 0.910 |
ykfB | ykfG | b0250 | b0247 | CP4-6 prophage; uncharacterized protein; To E.coli YfjT. | CP4-6 prophage; Putative DNA repair protein; Belongs to the UPF0758 family. | 0.624 |