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pepA pepA glyA glyA Ctha_1507 Ctha_1507 Ctha_1198 Ctha_1198 Ctha_1280 Ctha_1280 Ctha_2095 Ctha_2095 Ctha_0463 Ctha_0463 gmk gmk Ctha_0691 Ctha_0691 htpG htpG Ctha_0752 Ctha_0752
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pepALeucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (509 aa)    
Predicted Functional Partners:
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.838
Ctha_1507
TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cte:CT0700 cysteine synthase.
   
 0.832
Ctha_1198
PFAM: aminotransferase class I and II; KEGG: cte:CT0966 aspartate aminotransferase, putative.
   
  0.822
Ctha_1280
KEGG: ava:Ava_4077 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase.
     
  0.800
Ctha_2095
PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: plt:Plut_0953 Dhh family protein.
       0.792
Ctha_0463
PFAM: deoxynucleoside kinase; KEGG: sru:SRU_0956 deoxyguanosine kinase/deoxyadenosine kinase subunit.
   
 0.761
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
 
  0.597
Ctha_0691
KEGG: mba:Mbar_A2449 hypothetical protein.
    
  0.494
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
   
    0.465
Ctha_0752
PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: mar:MAE_03610 tetratricopeptide repeat protein.
 
  
 0.444
Your Current Organism:
Chloroherpeton thalassium
NCBI taxonomy Id: 517418
Other names: C. thalassium ATCC 35110, Chloroherpeton thalassium ATCC 35110, Chloroherpeton thalassium str. ATCC 35110, Chloroherpeton thalassium strain ATCC 35110
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