node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PC1_0098 | coaD | PC1_0098 | PC1_4095 | Methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.773 |
PC1_1017 | PC1_4101 | PC1_1017 | PC1_4101 | (Acyl-carrier-protein) phosphodiesterase; PFAM: protein of unknown function DUF479; KEGG: eca:ECA1118 hypothetical protein. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.900 |
PC1_1017 | coaA | PC1_1017 | PC1_0196 | (Acyl-carrier-protein) phosphodiesterase; PFAM: protein of unknown function DUF479; KEGG: eca:ECA1118 hypothetical protein. | TIGRFAM: pantothenate kinase; KEGG: eca:ECA0215 pantothenate kinase. | 0.908 |
PC1_1017 | coaD | PC1_1017 | PC1_4095 | (Acyl-carrier-protein) phosphodiesterase; PFAM: protein of unknown function DUF479; KEGG: eca:ECA1118 hypothetical protein. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.903 |
PC1_3654 | PC1_4101 | PC1_3654 | PC1_4101 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; cytidylyltransferase; Riboflavin kinase; KEGG: eca:ECA3877 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.620 |
PC1_3654 | coaD | PC1_3654 | PC1_4095 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; cytidylyltransferase; Riboflavin kinase; KEGG: eca:ECA3877 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.672 |
PC1_3654 | coaE | PC1_3654 | PC1_3579 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; cytidylyltransferase; Riboflavin kinase; KEGG: eca:ECA3877 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.561 |
PC1_3654 | guaA | PC1_3654 | PC1_3003 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; cytidylyltransferase; Riboflavin kinase; KEGG: eca:ECA3877 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.509 |
PC1_4093 | PC1_4094 | PC1_4093 | PC1_4094 | PFAM: glycosyl transferase family 2; KEGG: eca:ECA0153 lipopolysaccharide core biosynthesis glycosyl transferase. | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.671 |
PC1_4093 | coaD | PC1_4093 | PC1_4095 | PFAM: glycosyl transferase family 2; KEGG: eca:ECA0153 lipopolysaccharide core biosynthesis glycosyl transferase. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.607 |
PC1_4094 | PC1_4093 | PC1_4094 | PC1_4093 | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | PFAM: glycosyl transferase family 2; KEGG: eca:ECA0153 lipopolysaccharide core biosynthesis glycosyl transferase. | 0.671 |
PC1_4094 | coaD | PC1_4094 | PC1_4095 | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.742 |
PC1_4101 | PC1_1017 | PC1_4101 | PC1_1017 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | (Acyl-carrier-protein) phosphodiesterase; PFAM: protein of unknown function DUF479; KEGG: eca:ECA1118 hypothetical protein. | 0.900 |
PC1_4101 | PC1_3654 | PC1_4101 | PC1_3654 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; cytidylyltransferase; Riboflavin kinase; KEGG: eca:ECA3877 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.620 |
PC1_4101 | coaA | PC1_4101 | PC1_0196 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | TIGRFAM: pantothenate kinase; KEGG: eca:ECA0215 pantothenate kinase. | 0.936 |
PC1_4101 | coaD | PC1_4101 | PC1_4095 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.943 |
PC1_4101 | coaE | PC1_4101 | PC1_3579 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.592 |
coaA | PC1_1017 | PC1_0196 | PC1_1017 | TIGRFAM: pantothenate kinase; KEGG: eca:ECA0215 pantothenate kinase. | (Acyl-carrier-protein) phosphodiesterase; PFAM: protein of unknown function DUF479; KEGG: eca:ECA1118 hypothetical protein. | 0.908 |
coaA | PC1_4101 | PC1_0196 | PC1_4101 | TIGRFAM: pantothenate kinase; KEGG: eca:ECA0215 pantothenate kinase. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.936 |
coaA | coaD | PC1_0196 | PC1_4095 | TIGRFAM: pantothenate kinase; KEGG: eca:ECA0215 pantothenate kinase. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.927 |