node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Srot_0301 | Srot_0302 | Srot_0301 | Srot_0302 | TIGRFAM: serine O-acetyltransferase; KEGG: rer:RER_10920 serine acetyltransferase. | KEGG: rer:RER_10910 cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.996 |
Srot_0301 | mshC | Srot_0301 | Srot_1222 | TIGRFAM: serine O-acetyltransferase; KEGG: rer:RER_10920 serine acetyltransferase. | cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | 0.916 |
Srot_0302 | Srot_0301 | Srot_0302 | Srot_0301 | KEGG: rer:RER_10910 cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | TIGRFAM: serine O-acetyltransferase; KEGG: rer:RER_10920 serine acetyltransferase. | 0.996 |
Srot_0302 | mshC | Srot_0302 | Srot_1222 | KEGG: rer:RER_10910 cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. | cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | 0.816 |
Srot_0432 | glmM | Srot_0432 | Srot_0345 | Lsr2; KEGG: mjl:Mjls_5143 Lsr2. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.711 |
Srot_0432 | mshC | Srot_0432 | Srot_1222 | Lsr2; KEGG: mjl:Mjls_5143 Lsr2. | cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | 0.724 |
Srot_0432 | rpoZ | Srot_0432 | Srot_2295 | Lsr2; KEGG: mjl:Mjls_5143 Lsr2. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.843 |
Srot_1588 | glmM | Srot_1588 | Srot_0345 | PFAM: glycosyl transferase family 2; KEGG: rop:ROP_60290 putative glucosyl-3- phosphoglycerate synthase. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.818 |
Srot_1588 | mshC | Srot_1588 | Srot_1222 | PFAM: glycosyl transferase family 2; KEGG: rop:ROP_60290 putative glucosyl-3- phosphoglycerate synthase. | cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | 0.779 |
Srot_1588 | rpoZ | Srot_1588 | Srot_2295 | PFAM: glycosyl transferase family 2; KEGG: rop:ROP_60290 putative glucosyl-3- phosphoglycerate synthase. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.809 |
glmM | Srot_0432 | Srot_0345 | Srot_0432 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Lsr2; KEGG: mjl:Mjls_5143 Lsr2. | 0.711 |
glmM | Srot_1588 | Srot_0345 | Srot_1588 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | PFAM: glycosyl transferase family 2; KEGG: rop:ROP_60290 putative glucosyl-3- phosphoglycerate synthase. | 0.818 |
glmM | mshC | Srot_0345 | Srot_1222 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | 0.820 |
glmM | rpoZ | Srot_0345 | Srot_2295 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.822 |
mca | mshA | Srot_1977 | Srot_2070 | Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | UDP-N-acetylglucosamine; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. | 0.819 |
mca | mshB | Srot_1977 | Srot_0833 | Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- glucopyranosidede acetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. | 0.452 |
mca | mshC | Srot_1977 | Srot_1222 | Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | 0.833 |
mca | mshD | Srot_1977 | Srot_3047 | Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | Mycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol. | 0.877 |
mshA | mca | Srot_2070 | Srot_1977 | UDP-N-acetylglucosamine; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. | Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | 0.819 |
mshA | mshB | Srot_2070 | Srot_0833 | UDP-N-acetylglucosamine; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. | 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- glucopyranosidede acetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. | 0.939 |