STRINGSTRING
ftsH ftsH folE folE BAI64882.1 BAI64882.1 BAI64965.1 BAI64965.1 clpX clpX BAI63982.1 BAI63982.1 rplB rplB rplC rplC rplQ rplQ rpmA rpmA rplS rplS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ftsHATP-dependent Zn protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. (756 aa)    
Predicted Functional Partners:
folE
GTP cyclohydrolase I.
  
    0.931
BAI64882.1
Membrane protease subunit; Stomatin/prohibitin homologs.
   
 0.890
BAI64965.1
Membrane protease subunit; Stomatin/prohibitin homolog.
   
 0.890
clpX
ATP-dependent protease Clp, ATPase subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
   
  
 0.830
BAI63982.1
Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
  
 0.828
rplB
Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
 
 0.795
rplC
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.788
rplQ
Ribosomal protein L17.
   
 
 0.778
rpmA
Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
  
 
 0.778
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
   0.774
Your Current Organism:
Rothia mucilaginosa
NCBI taxonomy Id: 680646
Other names: R. mucilaginosa DY-18, Rothia mucilaginosa DY-18, Rothia mucilaginosa str. DY-18, Rothia mucilaginosa strain DY-18
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