node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bgb | Bro | FBpp0303213 | FBpp0072643 | Big brother (Bgb) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bro in embryonic segmentation; Belongs to the CBF-beta family. | Brother (Bro) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bgb in embryonic segmentation. | 0.645 |
Bgb | Cul5 | FBpp0303213 | FBpp0084786 | Big brother (Bgb) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bro in embryonic segmentation; Belongs to the CBF-beta family. | FI20194p1; Cullin 5 (Cul5) is expressed in both neuronal and non-neuronal cells (such as in fusion sites of embryonic trachea). Reduction of the product of Cul5 in neuronal cells results in an increase in number of synaptic boutons in the larval neuromuscular junction; Belongs to the cullin family. | 0.898 |
Bgb | EloB | FBpp0303213 | FBpp0083354 | Big brother (Bgb) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bro in embryonic segmentation; Belongs to the CBF-beta family. | Elongin B (EloB) encodes an essential protein for development that participates in the control of wing cell identity. EloB, EloC and EloA encode for subunits of the Elongin complex, which interacts in vivo with the chromatin factor encoded by corto. | 0.863 |
Bgb | EloC | FBpp0303213 | FBpp0085725 | Big brother (Bgb) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bro in embryonic segmentation; Belongs to the CBF-beta family. | Elongin C (EloC) encodes an essential protein for development that participates in the control of wing cell identity. EloB, EloC and EloA encode for subunits of the Elongin complex, which interacts in vivo with the chromatin factor encoded by corto. | 0.891 |
Bgb | lz | FBpp0303213 | FBpp0071255 | Big brother (Bgb) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bro in embryonic segmentation; Belongs to the CBF-beta family. | Protein lozenge; Involved in prepatterning photoreceptor precursors in the developing eye; in the larval eye disk it defines a subset of cells as an equipotential group that is competent to respond to the sevenless developmental signal and another subset that confer proper photoreceptor identity by positively regulating the homeo box gene Bar. Involved in the aop/pnt dynamic in a Ras-dependent manner to regulate pros expression. Promotes apoptosis in the pupal eye by directly activating aos and klu. Also modulates hid- and rpr-mediated cell death. Regulates amos function in olfactory s [...] | 0.906 |
Bgb | run | FBpp0303213 | FBpp0311837 | Big brother (Bgb) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bro in embryonic segmentation; Belongs to the CBF-beta family. | Segmentation protein Runt; Runt (run) encodes an alpha-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It contributes to axon guidance, dendrite morphogenesis and germ-band extension. | 0.982 |
Bro | Bgb | FBpp0072643 | FBpp0303213 | Brother (Bro) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bgb in embryonic segmentation. | Big brother (Bgb) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bro in embryonic segmentation; Belongs to the CBF-beta family. | 0.645 |
Bro | Bsg25A | FBpp0072643 | FBpp0077114 | Brother (Bro) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bgb in embryonic segmentation. | Early boundary activity protein 1; The heterotrimeric Elba complex is required for chromatin domain boundary function during early embryogenesis. It binds to a 8-bp sequence 5'-CCAATAAG-3' in the Fab-7 insulator or boundary element in the bithorax complex and contributes to its insulator or boundary activity. Elba1 may act as a transcriptional repressor and binds the palindromic sequence 5'-CCAATTGG-3' to mediate transcriptional repression. | 0.843 |
Bro | CG6962 | FBpp0072643 | FBpp0081990 | Brother (Bro) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bgb in embryonic segmentation. | LD28817p; Sphingomyelin phosphodiesterase D activity. It is involved in the biological process described with: ceramide biosynthetic process; glycerophospholipid catabolic process; sphingomyelin catabolic process. | 0.834 |
Bro | Cul5 | FBpp0072643 | FBpp0084786 | Brother (Bro) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bgb in embryonic segmentation. | FI20194p1; Cullin 5 (Cul5) is expressed in both neuronal and non-neuronal cells (such as in fusion sites of embryonic trachea). Reduction of the product of Cul5 in neuronal cells results in an increase in number of synaptic boutons in the larval neuromuscular junction; Belongs to the cullin family. | 0.898 |
Bro | Elba3 | FBpp0072643 | FBpp0077070 | Brother (Bro) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bgb in embryonic segmentation. | Early boundary activity protein 3; The heterotrimeric Elba complex is required for chromatin domain boundary function during early embryogenesis. It binds to a 8-bp sequence 5'-CCAATAAG-3' in the Fab-7 insulator or boundary element in the bithorax complex and contributes to its insulator or boundary activity. Elba3 lacks DNA-binding activity and plays the role of an adapter protein, bringing Elba1 and 2 together, thereby establishing a complex that recognizes the asymmetric sequence motif through the BEN domains of Elba1 and 2. | 0.703 |
Bro | EloB | FBpp0072643 | FBpp0083354 | Brother (Bro) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bgb in embryonic segmentation. | Elongin B (EloB) encodes an essential protein for development that participates in the control of wing cell identity. EloB, EloC and EloA encode for subunits of the Elongin complex, which interacts in vivo with the chromatin factor encoded by corto. | 0.860 |
Bro | EloC | FBpp0072643 | FBpp0085725 | Brother (Bro) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bgb in embryonic segmentation. | Elongin C (EloC) encodes an essential protein for development that participates in the control of wing cell identity. EloB, EloC and EloA encode for subunits of the Elongin complex, which interacts in vivo with the chromatin factor encoded by corto. | 0.889 |
Bro | Pif2 | FBpp0072643 | FBpp0081176 | Brother (Bro) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bgb in embryonic segmentation. | Protein binding. | 0.668 |
Bro | lz | FBpp0072643 | FBpp0071255 | Brother (Bro) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bgb in embryonic segmentation. | Protein lozenge; Involved in prepatterning photoreceptor precursors in the developing eye; in the larval eye disk it defines a subset of cells as an equipotential group that is competent to respond to the sevenless developmental signal and another subset that confer proper photoreceptor identity by positively regulating the homeo box gene Bar. Involved in the aop/pnt dynamic in a Ras-dependent manner to regulate pros expression. Promotes apoptosis in the pupal eye by directly activating aos and klu. Also modulates hid- and rpr-mediated cell death. Regulates amos function in olfactory s [...] | 0.672 |
Bro | run | FBpp0072643 | FBpp0311837 | Brother (Bro) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bgb in embryonic segmentation. | Segmentation protein Runt; Runt (run) encodes an alpha-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It contributes to axon guidance, dendrite morphogenesis and germ-band extension. | 0.887 |
Bsg25A | Bro | FBpp0077114 | FBpp0072643 | Early boundary activity protein 1; The heterotrimeric Elba complex is required for chromatin domain boundary function during early embryogenesis. It binds to a 8-bp sequence 5'-CCAATAAG-3' in the Fab-7 insulator or boundary element in the bithorax complex and contributes to its insulator or boundary activity. Elba1 may act as a transcriptional repressor and binds the palindromic sequence 5'-CCAATTGG-3' to mediate transcriptional repression. | Brother (Bro) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bgb in embryonic segmentation. | 0.843 |
Bsg25A | Elba3 | FBpp0077114 | FBpp0077070 | Early boundary activity protein 1; The heterotrimeric Elba complex is required for chromatin domain boundary function during early embryogenesis. It binds to a 8-bp sequence 5'-CCAATAAG-3' in the Fab-7 insulator or boundary element in the bithorax complex and contributes to its insulator or boundary activity. Elba1 may act as a transcriptional repressor and binds the palindromic sequence 5'-CCAATTGG-3' to mediate transcriptional repression. | Early boundary activity protein 3; The heterotrimeric Elba complex is required for chromatin domain boundary function during early embryogenesis. It binds to a 8-bp sequence 5'-CCAATAAG-3' in the Fab-7 insulator or boundary element in the bithorax complex and contributes to its insulator or boundary activity. Elba3 lacks DNA-binding activity and plays the role of an adapter protein, bringing Elba1 and 2 together, thereby establishing a complex that recognizes the asymmetric sequence motif through the BEN domains of Elba1 and 2. | 0.999 |
CG6962 | Bro | FBpp0081990 | FBpp0072643 | LD28817p; Sphingomyelin phosphodiesterase D activity. It is involved in the biological process described with: ceramide biosynthetic process; glycerophospholipid catabolic process; sphingomyelin catabolic process. | Brother (Bro) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bgb in embryonic segmentation. | 0.834 |
Cul5 | Bgb | FBpp0084786 | FBpp0303213 | FI20194p1; Cullin 5 (Cul5) is expressed in both neuronal and non-neuronal cells (such as in fusion sites of embryonic trachea). Reduction of the product of Cul5 in neuronal cells results in an increase in number of synaptic boutons in the larval neuromuscular junction; Belongs to the cullin family. | Big brother (Bgb) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bro in embryonic segmentation; Belongs to the CBF-beta family. | 0.898 |