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ox ox UQCR-14 UQCR-14 UQCR-C2 UQCR-C2 Cyt-c1 Cyt-c1 COX5A COX5A UQCR-C1 UQCR-C1 UQCR-11 UQCR-11 UQCR-Q UQCR-Q UQCR-6.4 UQCR-6.4 RFeSP RFeSP COX7C COX7C
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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oxCytochrome b-c1 complex subunit 9; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inn [...] (55 aa)    
Predicted Functional Partners:
UQCR-14
Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family.
   
 0.999
UQCR-C2
Endopeptidase activity; metal ion binding; ubiquinol-cytochrome-c reductase activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c; protein processing involved in protein targeting to mitochondrion.
   
 0.999
Cyt-c1
Cytochrome c1, isoform A; Heme binding; electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c; mitochondrial ATP synthesis coupled proton transport.
   
 0.999
COX5A
Cytochrome c oxidase subunit 5A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...]
   
 0.999
UQCR-C1
Metalloendopeptidase activity; ubiquinol-cytochrome-c reductase activity; metal ion binding; endopeptidase activity. It is involved in the biological process described with: protein processing; protein processing involved in protein targeting to mitochondrion; mitochondrial electron transport, ubiquinol to cytochrome c.
   
 0.999
UQCR-11
Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family.
   
 0.999
UQCR-Q
Ubiquinol-cytochrome-c reductase activity; ubiquinone binding. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c.
   
 0.999
UQCR-6.4
Ubiquinol-cytochrome-c reductase activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c.
   
 0.999
RFeSP
Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
   
 0.999
COX7C
Cytochrome c oxidase subunit 7C (COX7C) encodes a negative regulator of neuroblast proliferation.
   
 0.999
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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