node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Actbeta | Con | FBpp0088273 | FBpp0301699 | Inhibin beta chain; Controls several aspects of neuronal morphogenesis; essential for optic lobe development, EcR-B1 expression in larval brains, mushroom body remodeling, dorsal neuron morphogenesis and motoneuron axon guidance. Ligands Actbeta and daw act redundantly through the Activin receptor Babo and its transcriptional mediator Smad2 (Smox), to regulate neuroblast numbers and proliferation rates in the developing larval brain; Belongs to the TGF-beta family. | Connectin; Cell adhesion protein involved in target recognition during neuromuscular development. Mediates homophilic cellular adhesion. | 0.589 |
Cirl | Con | FBpp0302596 | FBpp0301699 | Latrophilin Cirl; Latrotoxin receptor activity; G protein-coupled receptor activity; carbohydrate binding; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | Connectin; Cell adhesion protein involved in target recognition during neuromuscular development. Mediates homophilic cellular adhesion. | 0.636 |
Con | Actbeta | FBpp0301699 | FBpp0088273 | Connectin; Cell adhesion protein involved in target recognition during neuromuscular development. Mediates homophilic cellular adhesion. | Inhibin beta chain; Controls several aspects of neuronal morphogenesis; essential for optic lobe development, EcR-B1 expression in larval brains, mushroom body remodeling, dorsal neuron morphogenesis and motoneuron axon guidance. Ligands Actbeta and daw act redundantly through the Activin receptor Babo and its transcriptional mediator Smad2 (Smox), to regulate neuroblast numbers and proliferation rates in the developing larval brain; Belongs to the TGF-beta family. | 0.589 |
Con | Cirl | FBpp0301699 | FBpp0302596 | Connectin; Cell adhesion protein involved in target recognition during neuromuscular development. Mediates homophilic cellular adhesion. | Latrophilin Cirl; Latrotoxin receptor activity; G protein-coupled receptor activity; carbohydrate binding; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | 0.636 |
Con | DopEcR | FBpp0301699 | FBpp0099542 | Connectin; Cell adhesion protein involved in target recognition during neuromuscular development. Mediates homophilic cellular adhesion. | Dopamine/Ecdysteroid receptor (DopEcR) encodes a GPCR that shows ligand-biased activation. It can be activated by dopamine to increase cyclic AMP levels and by the insect steroid ecdysone to activate the MAPKinase pathway. It is widely expressed in the nervous system and can modulate a wide variety of complex behaviors including male courtship, locomotion, the response to stressful social interactions and the regulation of appetite. | 0.574 |
Con | Fas2 | FBpp0301699 | FBpp0310127 | Connectin; Cell adhesion protein involved in target recognition during neuromuscular development. Mediates homophilic cellular adhesion. | Fasciclin-2; Neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles. | 0.708 |
Con | Fas3 | FBpp0301699 | FBpp0111717 | Connectin; Cell adhesion protein involved in target recognition during neuromuscular development. Mediates homophilic cellular adhesion. | Fasciclin-3; Mediates cell adhesion in a Ca(2+)-independent manner. It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system. | 0.608 |
Con | Mys45A | FBpp0301699 | FBpp0087709 | Connectin; Cell adhesion protein involved in target recognition during neuromuscular development. Mediates homophilic cellular adhesion. | Protein SDA1 homolog; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. | 0.629 |
Con | NetB | FBpp0301699 | FBpp0291228 | Connectin; Cell adhesion protein involved in target recognition during neuromuscular development. Mediates homophilic cellular adhesion. | Netrin-B; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either fra or unc-5 receptors will lead to axon attraction or repulsion, respectively. While short-range repulsion requires both fra and unc-5 receptors, long-range repulsion only requires unc-5. | 0.691 |
Con | fne | FBpp0301699 | FBpp0297664 | Connectin; Cell adhesion protein involved in target recognition during neuromuscular development. Mediates homophilic cellular adhesion. | Found in neurons (fne) encodes an RNA binding protein that works as a post-transcriptional regulator. It is present in the cytoplasm of all neurons. Lack of fne produces fusion of the mushroom body beta-lobes and altered male courtship behaviour. | 0.666 |
Con | mspo | FBpp0301699 | FBpp0311552 | Connectin; Cell adhesion protein involved in target recognition during neuromuscular development. Mediates homophilic cellular adhesion. | M-spondin, isoform A; It is involved in the biological process described with: cell adhesion; regulation of myoblast fusion. | 0.612 |
Con | robo1 | FBpp0301699 | FBpp0309765 | Connectin; Cell adhesion protein involved in target recognition during neuromuscular development. Mediates homophilic cellular adhesion. | Roundabout 1 (robo1) encodes a member of the Robo receptor family that uses the secreted glycoprotein encoded by sli as ligand and the products of Sdc and Dscam1 as co-receptors. It contributes to axon guidance and dendrite morphogenesis as well as regulating trachea and heart tube development. | 0.549 |
DopEcR | Con | FBpp0099542 | FBpp0301699 | Dopamine/Ecdysteroid receptor (DopEcR) encodes a GPCR that shows ligand-biased activation. It can be activated by dopamine to increase cyclic AMP levels and by the insect steroid ecdysone to activate the MAPKinase pathway. It is widely expressed in the nervous system and can modulate a wide variety of complex behaviors including male courtship, locomotion, the response to stressful social interactions and the regulation of appetite. | Connectin; Cell adhesion protein involved in target recognition during neuromuscular development. Mediates homophilic cellular adhesion. | 0.574 |
DopEcR | fne | FBpp0099542 | FBpp0297664 | Dopamine/Ecdysteroid receptor (DopEcR) encodes a GPCR that shows ligand-biased activation. It can be activated by dopamine to increase cyclic AMP levels and by the insect steroid ecdysone to activate the MAPKinase pathway. It is widely expressed in the nervous system and can modulate a wide variety of complex behaviors including male courtship, locomotion, the response to stressful social interactions and the regulation of appetite. | Found in neurons (fne) encodes an RNA binding protein that works as a post-transcriptional regulator. It is present in the cytoplasm of all neurons. Lack of fne produces fusion of the mushroom body beta-lobes and altered male courtship behaviour. | 0.437 |
Fas2 | Con | FBpp0310127 | FBpp0301699 | Fasciclin-2; Neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles. | Connectin; Cell adhesion protein involved in target recognition during neuromuscular development. Mediates homophilic cellular adhesion. | 0.708 |
Fas2 | Fas3 | FBpp0310127 | FBpp0111717 | Fasciclin-2; Neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles. | Fasciclin-3; Mediates cell adhesion in a Ca(2+)-independent manner. It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system. | 0.832 |
Fas2 | NetB | FBpp0310127 | FBpp0291228 | Fasciclin-2; Neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles. | Netrin-B; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either fra or unc-5 receptors will lead to axon attraction or repulsion, respectively. While short-range repulsion requires both fra and unc-5 receptors, long-range repulsion only requires unc-5. | 0.622 |
Fas2 | robo1 | FBpp0310127 | FBpp0309765 | Fasciclin-2; Neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles. | Roundabout 1 (robo1) encodes a member of the Robo receptor family that uses the secreted glycoprotein encoded by sli as ligand and the products of Sdc and Dscam1 as co-receptors. It contributes to axon guidance and dendrite morphogenesis as well as regulating trachea and heart tube development. | 0.432 |
Fas3 | Con | FBpp0111717 | FBpp0301699 | Fasciclin-3; Mediates cell adhesion in a Ca(2+)-independent manner. It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system. | Connectin; Cell adhesion protein involved in target recognition during neuromuscular development. Mediates homophilic cellular adhesion. | 0.608 |
Fas3 | Fas2 | FBpp0111717 | FBpp0310127 | Fasciclin-3; Mediates cell adhesion in a Ca(2+)-independent manner. It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system. | Fasciclin-2; Neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles. | 0.832 |