STRINGSTRING
ENSXETP00000028394 ENSXETP00000028394 fmnl2 fmnl2 tmc4 tmc4 znf518a znf518a wdr5 wdr5 mcrs1 mcrs1 ENSXETP00000028716 ENSXETP00000028716 commd4 commd4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ENSXETP00000028394ATPase family AAA domain-containing protein 3. (324 aa)    
Predicted Functional Partners:
fmnl2
Glutamate-cysteine ligase, modifier subunit.
     
  0.800
tmc4
Transmembrane channel like 4.
     
  0.800
znf518a
Ubiquitin specific peptidase 49.
     
  0.800
wdr5
WD repeat-containing protein 5; Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation (By similarity).
     
  0.800
mcrs1
Microspherule protein 1.
     
  0.800
ENSXETP00000028716
Uncharacterized protein.
      
 0.571
commd4
COMM domain-containing protein.
     
  0.400
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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