STRINGSTRING
JAG1 JAG1 NOTCH1 NOTCH1 NOTCH2 NOTCH2 JAG2 JAG2 RBPJ RBPJ HEY1 HEY1 MAML2 MAML2 HEY2 HEY2 MAML3 MAML3 ADAM10 ADAM10 LFNG LFNG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1216 aa)    
Predicted Functional Partners:
NOTCH1
Uncharacterized protein.
   
0.999
NOTCH2
Uncharacterized protein.
   
0.989
JAG2
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
  
0.935
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 
 0.899
HEY1
Hes related family bHLH transcription factor with YRPW motif 1.
    
 
 0.859
MAML2
Mastermind like transcriptional coactivator 2.
   
 
 0.811
HEY2
Hes related family bHLH transcription factor with YRPW motif 2.
    
 
 0.780
MAML3
MamL-1 domain-containing protein.
    
 
 0.777
ADAM10
Uncharacterized protein.
    
 0.735
LFNG
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Essential mediator of somite segmentation and patterning.
    
 
 0.734
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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