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hemE hemE hemC hemC hemF hemF ABK50333.1 ABK50333.1 ABK46628.1 ABK46628.1 ABK47100.1 ABK47100.1 ABK46627.1 ABK46627.1 hemH-2 hemH-2 hemH hemH ABK49952.1 ABK49952.1 ABK49274.1 ABK49274.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (354 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.984
hemF
Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
 
 0.965
ABK50333.1
KEGG: son:SO4730 oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
 
 
 0.950
ABK46628.1
Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
 
 0.942
ABK47100.1
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: son:SO3728 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
    
 0.940
ABK46627.1
PFAM: protein of unknown function DUF513, hemX; KEGG: son:SO4315 hemX protein.
    
 0.910
hemH-2
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.829
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.820
ABK49952.1
PFAM: delta-aminolevulinic acid dehydratase; KEGG: son:SO4208 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.736
ABK49274.1
PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: son:SO1325 glutamate synthase (NADPH) large chain.
 
   
 0.709
Your Current Organism:
Shewanella sp. ANA3
NCBI taxonomy Id: 94122
Other names: S. sp. ANA-3, Shewanella sp. ANA-3, Shewanella sp. arsenana, Shewanella trabarsenatis
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