node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MRPL12 | MRPL17 | ENSP00000333837 | ENSP00000288937 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | Mitochondrial ribosomal protein L17. | 0.999 |
MRPL12 | MRPL27 | ENSP00000333837 | ENSP00000225969 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | Mitochondrial ribosomal protein L27. | 0.999 |
MRPL12 | MRPL32 | ENSP00000333837 | ENSP00000223324 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | Mitochondrial ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.999 |
MRPL12 | MRPL33 | ENSP00000333837 | ENSP00000296102 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | Mitochondrial ribosomal protein L33. | 0.999 |
MRPL12 | MRPS7 | ENSP00000333837 | ENSP00000245539 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | Mitochondrial ribosomal protein S7. | 0.997 |
MRPL12 | MRPS9 | ENSP00000333837 | ENSP00000258455 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | Mitochondrial ribosomal protein S9. | 0.999 |
MRPL12 | RPS11 | ENSP00000333837 | ENSP00000270625 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family. | 0.999 |
MRPL12 | RPS3 | ENSP00000333837 | ENSP00000278572 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro- 8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...] | 0.999 |
MRPL12 | TSFM | ENSP00000333837 | ENSP00000313877 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | Elongation factor Ts, mitochondrial; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.966 |
MRPL12 | TUFM | ENSP00000333837 | ENSP00000322439 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | Elongation factor Tu, mitochondrial; Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG- I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | 0.999 |
MRPL17 | MRPL12 | ENSP00000288937 | ENSP00000333837 | Mitochondrial ribosomal protein L17. | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | 0.999 |
MRPL17 | MRPL27 | ENSP00000288937 | ENSP00000225969 | Mitochondrial ribosomal protein L17. | Mitochondrial ribosomal protein L27. | 0.999 |
MRPL17 | MRPL32 | ENSP00000288937 | ENSP00000223324 | Mitochondrial ribosomal protein L17. | Mitochondrial ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.999 |
MRPL17 | MRPL33 | ENSP00000288937 | ENSP00000296102 | Mitochondrial ribosomal protein L17. | Mitochondrial ribosomal protein L33. | 0.999 |
MRPL17 | MRPS7 | ENSP00000288937 | ENSP00000245539 | Mitochondrial ribosomal protein L17. | Mitochondrial ribosomal protein S7. | 0.999 |
MRPL17 | MRPS9 | ENSP00000288937 | ENSP00000258455 | Mitochondrial ribosomal protein L17. | Mitochondrial ribosomal protein S9. | 0.999 |
MRPL17 | RPS11 | ENSP00000288937 | ENSP00000270625 | Mitochondrial ribosomal protein L17. | Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family. | 0.999 |
MRPL17 | RPS3 | ENSP00000288937 | ENSP00000278572 | Mitochondrial ribosomal protein L17. | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro- 8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...] | 0.999 |
MRPL17 | TSFM | ENSP00000288937 | ENSP00000313877 | Mitochondrial ribosomal protein L17. | Elongation factor Ts, mitochondrial; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.958 |
MRPL17 | TUFM | ENSP00000288937 | ENSP00000322439 | Mitochondrial ribosomal protein L17. | Elongation factor Tu, mitochondrial; Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG- I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | 0.999 |