STRINGSTRING
POM121L2 POM121L2 POM121 POM121 POM121C POM121C NT5C2 NT5C2 PRSS16 PRSS16 ZNF184 ZNF184 OR14J1 OR14J1 SLC17A1 SLC17A1 CNNM2 CNNM2 HMGN4 HMGN4 AS3MT AS3MT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
POM121L2POM121-like protein 2; POM121 transmembrane nucleoporin like 2; Belongs to the POM121 family. (1035 aa)    
Predicted Functional Partners:
POM121
Nuclear envelope pore membrane protein POM 121; Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL).
     
0.904
POM121C
Nuclear envelope pore membrane protein POM 121C; Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL). Belongs to the POM121 family.
     
 
0.900
NT5C2
Cytosolic purine 5'-nucleotidase; May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.
      
 0.617
PRSS16
Thymus-specific serine protease; Protease that may play a role in T-cell development; Belongs to the peptidase S28 family.
      
 0.613
ZNF184
Zinc finger protein 184; May be involved in transcriptional regulation.
      
 0.571
OR14J1
Olfactory receptor 14J1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.501
SLC17A1
Sodium-dependent phosphate transport protein 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Plays a role in urate transport in the kidney.
      
 0.491
CNNM2
Metal transporter CNNM2; Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity).
      
 0.488
HMGN4
High mobility group nucleosomal binding domain 4; Belongs to the HMGN family.
      
 0.472
AS3MT
Arsenite methyltransferase; Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH.
      
 0.463
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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