STRINGSTRING
H2AC16 H2AC16 H2BC4 H2BC4 H2BC8 H2BC8 H4C13 H4C13 H2BC10 H2BC10 H4C2 H4C2 H4C14 H4C14 H4C4 H4C4 H4C11 H4C11 H2BC11 H2BC11 H4C1 H4C1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2AC16H2A clustered histone 16. (130 aa)    
Predicted Functional Partners:
H2BC4
Histone H2B type 1-C/E/F/G/I; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 
 0.976
H2BC8
H2B clustered histone 8.
 
 
 
 0.976
H4C13
H4 clustered histone 13.
 
 
 
 0.970
H2BC10
H2B clustered histone 10.
 
 
 
 0.969
H4C2
H4 clustered histone 2.
 
 
 
 0.968
H4C14
H4 clustered histone 14.
 
 
 
 0.967
H4C4
H4 clustered histone 4.
 
 
 
 0.967
H4C11
H4 clustered histone 11.
 
 
 
 0.966
H2BC11
Histone H2B type 1-J; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 
 0.966
H4C1
H4 clustered histone 1.
 
 
 
 0.966
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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