node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARMH3 | CNOT10 | ENSBTAP00000059381 | ENSBTAP00000006348 | Armadillo like helical domain containing 3. | CCR4-NOT transcription complex subunit 10. | 0.772 |
ARMH3 | NOL7 | ENSBTAP00000059381 | ENSBTAP00000028718 | Armadillo like helical domain containing 3. | Nucleolar protein 7, 27kDa. | 0.772 |
ARMH3 | NUBP1 | ENSBTAP00000059381 | ENSBTAP00000012576 | Armadillo like helical domain containing 3. | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.625 |
CIAO1 | CIAO3 | ENSBTAP00000020797 | ENSBTAP00000003225 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity). As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures AC [...] | Cytosolic iron-sulfur assembly component 3; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect (By similarity). | 0.983 |
CIAO1 | NUBP1 | ENSBTAP00000020797 | ENSBTAP00000012576 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity). As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures AC [...] | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.709 |
CIAO3 | CIAO1 | ENSBTAP00000003225 | ENSBTAP00000020797 | Cytosolic iron-sulfur assembly component 3; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect (By similarity). | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity). As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures AC [...] | 0.983 |
CIAO3 | NUBP1 | ENSBTAP00000003225 | ENSBTAP00000012576 | Cytosolic iron-sulfur assembly component 3; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect (By similarity). | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.722 |
CNOT10 | ARMH3 | ENSBTAP00000006348 | ENSBTAP00000059381 | CCR4-NOT transcription complex subunit 10. | Armadillo like helical domain containing 3. | 0.772 |
CNOT10 | NOL7 | ENSBTAP00000006348 | ENSBTAP00000028718 | CCR4-NOT transcription complex subunit 10. | Nucleolar protein 7, 27kDa. | 0.791 |
CNOT10 | NUBP1 | ENSBTAP00000006348 | ENSBTAP00000012576 | CCR4-NOT transcription complex subunit 10. | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.646 |
CNOT10 | SF3A3 | ENSBTAP00000006348 | ENSBTAP00000065151 | CCR4-NOT transcription complex subunit 10. | Splicing factor 3a, subunit 3, 60kDa. | 0.500 |
NOL7 | ARMH3 | ENSBTAP00000028718 | ENSBTAP00000059381 | Nucleolar protein 7, 27kDa. | Armadillo like helical domain containing 3. | 0.772 |
NOL7 | CNOT10 | ENSBTAP00000028718 | ENSBTAP00000006348 | Nucleolar protein 7, 27kDa. | CCR4-NOT transcription complex subunit 10. | 0.791 |
NOL7 | NUBP1 | ENSBTAP00000028718 | ENSBTAP00000012576 | Nucleolar protein 7, 27kDa. | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.708 |
NOL7 | SF3A3 | ENSBTAP00000028718 | ENSBTAP00000065151 | Nucleolar protein 7, 27kDa. | Splicing factor 3a, subunit 3, 60kDa. | 0.427 |
NSFL1C | NUBP1 | ENSBTAP00000008580 | ENSBTAP00000012576 | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.813 |
NUBP1 | ARMH3 | ENSBTAP00000012576 | ENSBTAP00000059381 | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | Armadillo like helical domain containing 3. | 0.625 |
NUBP1 | CIAO1 | ENSBTAP00000012576 | ENSBTAP00000020797 | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity). As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures AC [...] | 0.709 |
NUBP1 | CIAO3 | ENSBTAP00000012576 | ENSBTAP00000003225 | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | Cytosolic iron-sulfur assembly component 3; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect (By similarity). | 0.722 |
NUBP1 | CNOT10 | ENSBTAP00000012576 | ENSBTAP00000006348 | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | CCR4-NOT transcription complex subunit 10. | 0.646 |