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guaA guaA sll1499 sll1499 smpB smpB gltB gltB pnp pnp prfB prfB prfC prfC IAP75 IAP75 prfA prfA slr1229 slr1229 slr1230 slr1230
"prfC" - Peptide-chain-release factor 3 in Synechocystis sp. PCC6803
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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prfCPeptide-chain-release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) (547 aa)    
Predicted Functional Partners:
prfA
Peptide chain release factor; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (365 aa)
     
 
  0.793
prfB
Peptide chain release factor; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (335 aa)
   
   
  0.745
slr1229
Hypothetical protein (498 aa)
              0.703
sll1499
Ferredoxin-dependent glutamate synthase (1556 aa)
           
  0.613
gltB
Ferredoxin-dependent glutamate synthase (1550 aa)
           
  0.613
IAP75
Chloroplast import-associated channel IAP75 (861 aa)
              0.571
slr1230
Hypothetical protein (287 aa)
              0.490
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP (523 aa)
   
   
  0.437
smpB
Small protein; Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a ’tag peptide’, a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to transl [...] (154 aa)
     
      0.436
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3’- to 5’-direction (718 aa)
   
   
  0.417
Your Current Organism:
Synechocystis sp. PCC6803
NCBI taxonomy Id: 1148
Other names: Aphanocapsa sp. (strain N-1), Aphanocapsa sp. N-1, S. sp. PCC 6803, Synechocystis, Synechocystis PCC6803, Synechocystis sp. (ATCC 27184), Synechocystis sp. (PCC 6803), Synechocystis sp. (strain PCC 6803), Synechocystis sp. ATCC 27184, Synechocystis sp. PCC 6803, Synechocystis sp. PCC 6803 A, Synechocystis sp. PCC 6803 B, Synechocystis sp. PCC6803
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