Full Link:
STRINGSTRING
cobQ cobQ cobU cobU cobD cobD sll1500 sll1500 cbiE cbiE SYNGTS_0883 SYNGTS_0883 cobS cobS cbiH cbiH cobO cobO gpmB gpmB slr1748 slr1748
"cobS" - Cobalamin synthase CobS in Synechocystis sp. PCC6803
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobSCobalamin synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5’-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5’-phosphate (260 aa)    
Predicted Functional Partners:
cobU
Cobinamide kinase/cobinamide phosphate guanylyltransferase (185 aa)
 
 
  0.999
cobO
cob(I)yrinic acid a,c-diamide adenosyltransferase (203 aa)
 
 
  0.973
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) (498 aa)
 
   
  0.942
cobD
Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (342 aa)
 
   
  0.918
SYNGTS_0883
Histidinol-phosphate aminotransferase (368 aa)
 
 
  0.871
gpmB
Phosphoglycerate mutase (443 aa)
   
 
  0.870
cbiH
Precorrin methylase (627 aa)
   
   
  0.863
sll1500
Hypothetical protein (369 aa)
   
 
  0.855
slr1748
Hypothetical protein (214 aa)
 
 
  0.854
cbiE
Precorrin-6y C5,15-methyltransferase (decarboxylating) (425 aa)
   
   
  0.842
Your Current Organism:
Synechocystis sp. PCC6803
NCBI taxonomy Id: 1148
Other names: Aphanocapsa sp. (strain N-1), Aphanocapsa sp. N-1, S. sp. PCC 6803, Synechocystis, Synechocystis PCC6803, Synechocystis sp. (ATCC 27184), Synechocystis sp. (PCC 6803), Synechocystis sp. (strain PCC 6803), Synechocystis sp. ATCC 27184, Synechocystis sp. PCC 6803, Synechocystis sp. PCC 6803 A, Synechocystis sp. PCC 6803 B, Synechocystis sp. PCC6803
Server load: low (2%)