Full Link:
STRINGSTRING
sll1582 sll1582 dnaN dnaN recQ recQ slr0789 slr0789 sbcC sbcC umuC umuC polA polA recA recA ruvC ruvC lexA lexA uvrA uvrA
"umuC" - UmuC protein in Synechocystis sp. PCC6803
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
umuCUmuC protein (116 aa)    
Predicted Functional Partners:
recA
Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (354 aa)
   
  0.993
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3’ to 5’ and 5’ to 3’ exonuclease activity (986 aa)
   
  0.983
dnaN
DNA polymerase III beta subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) (391 aa)
     
  0.966
lexA
SOS function regulatory protein LexA; A probable transcription regulator, probably involved in carbon metabolism (PubMed-15225304). Binds and probably regulates expression of bidirectional hydrogenase (hoxEFUHY), probably activates its transcription (PubMed-16102913, PubMed-16238629). A possible regulator of redox-responsive genes. Binds 2 direct repeats of the DNA with sequence 5’-CTA-N(9)-CTA-3’ in the upstream region of both its own gene (includes the transcription start site) and crhR (includes the initiation codon) in a sequence-specific manner; does not bind crhR RNA (PubMed-1855 [...] (203 aa)
   
  0.965
sll1582
Hypothetical protein (1118 aa)
     
 
  0.906
slr0789
Hypothetical protein (185 aa)
              0.824
ruvC
Holliday juction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5’-terminal phosphate and a 3’-terminal hydroxyl group (By similarity) (167 aa)
       
 
  0.808
sbcC
Hypothetical protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3’->5’ double strand exonuclease that can open hairpins. It also has a 5’ single-strand endonuclease activity (1006 aa)
     
  0.788
uvrA
Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (970 aa)
   
   
  0.787
recQ
ATP-dependent DNA helicase RecQ; DNA helicase (478 aa)
   
  0.784
Your Current Organism:
Synechocystis sp. PCC6803
NCBI taxonomy Id: 1148
Other names: Aphanocapsa sp. (strain N-1), Aphanocapsa sp. N-1, S. sp. PCC 6803, Synechocystis, Synechocystis PCC6803, Synechocystis sp. (ATCC 27184), Synechocystis sp. (PCC 6803), Synechocystis sp. (strain PCC 6803), Synechocystis sp. ATCC 27184, Synechocystis sp. PCC 6803, Synechocystis sp. PCC 6803 A, Synechocystis sp. PCC 6803 B, Synechocystis sp. PCC6803
Server load: low (2%)