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APEM9 APEM9 PEX10 PEX10 PEX7 PEX7 PEX22 PEX22 PEX5 PEX5 PEX14 PEX14 PEX12 PEX12 PEX19-1 PEX19-1 PEX1 PEX1 PEX13 PEX13 PEX6 PEX6
"PEX6" - Peroxin 6 in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
PEX6Peroxin 6; Involved in peroxisomal-targeting signal one (PTS1) and peroxisomal-targeting signal two (PTS2) protein import. Required for jasmonate biosynthesis. Necessary for the developmental elimination of obsolete peroxisome matix proteins. May form heteromeric AAA ATPase complexes required for the import of proteins. May be involved in PEX5 recycling (941 aa)    
Predicted Functional Partners:
PEX1
Peroxisome 1; Involved in PTS1- and PTS2-dependent protein import into peroxisomes. May form heteromeric AAA ATPase complexes required for the import of proteins (1130 aa)
   
0.997
PEX5
Peroxin 5; Import receptor for peroxisomal-targeting signal one (PTS1). A receptor-cargo complex composed of PEX5, PEX7, a PTS1- containing protein and a PTS2-containing protein is targeted to peroxisomes during import. Necessary for the developmental elimination of obsolete peroxisome matrix proteins (728 aa)
     
 
  0.977
PEX14
Peroxin 14; Controls intracellular transport of both PTS1- and PTS2- containing proteins. Required for the proper targeting of PEX7 to the peroxisome (507 aa)
     
 
  0.960
PEX12
Peroxin-12; Required for peroxisome biogenesis and for PTS1- and PTS2-dependent protein import into peroxisomes. Essential for the peroxisomal targeting of PEX7. Required for the export/release of receptors on the peroxisome membrane. Acts as an E3 ubiquitin- protein ligase involved in monoubiquitination of PEX5 (393 aa)
     
 
  0.958
PEX10
Peroxin 10; Involved in the formation of peroxisomes, lipid bodies and protein bodies. Required for normal-shaped peroxisomes that can physically associate with the outer membrane of the chloroplast envelope. Not involved in beta-oxidation and glyoxylate cycle. Acts as an E3 ubiquitin-protein ligase (381 aa)
     
 
  0.955
APEM9
ABERRANT PEROXISOME MORPHOLOGY 9 (333 aa)
     
 
  0.952
PEX7
Peroxin 7; Import receptor for peroxisomal-targeting signal two (PTS2). A receptor-cargo complex composed of PEX5, PEX7, a PTS1- containing protein and a PTS2-containing protein is targeted to peroxisomes during import (317 aa)
     
   
  0.951
PEX19-1
Peroxin 19-1; Contributes to morphology determination of peroxisomes, but not to import of peroxisomal matrix proteins. Required for proper post-translational import and stabilization of peroxisomal membrane proteins (PMPs). Acts as a cytosolic import receptor for PMPs and delivers them to the docking factor PEX3 at the peroxisomal membrane for subsequent insertion into the membrane. Acts as a chaperone in stabilizing or maintaining PMPs in the lipid bilayer (248 aa)
     
 
  0.909
PEX22
Peroxin 22; May tethered PEX4 to the peroxisome membrane and may be involved in a late step of the matrix protein import. Does not play a role in the biogenesis of the peroxisomal membrane (283 aa)
           
  0.879
PEX13
Peroxin 13; Involved in PTS1- and PTS2-dependent protein import into peroxisomes. Acts as a docking factor on peroxisomal membranes. Required for the proper targeting of PEX7 to the peroxisome. Required for the export/release of receptors on the peroxisome membrane (304 aa)
           
  0.863
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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