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RHM1 RHM1 DFR DFR TT4 TT4 UGT78D2 UGT78D2 CHIL CHIL FLS1 FLS1 F3H F3H 4CL3 4CL3 AT1G06000 AT1G06000 TT5 TT5 AT4G29440 AT4G29440
"AT1G06000" - UDP-glycosyltransferase-like protein in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
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[Homology]
Score
AT1G06000UDP-glycosyltransferase-like protein; Flavonol 7-O-rhamnosyltransferase that acts on kaempferol 3-O-glucoside and other 3-O-glycosylated flavonols like quercetin 3-O-glucoside, quercetin 3-O-galactoside and isorhamnetin 3-O-glucoside. Shows a strict specificity for UDP- rhamnose as donor and does not act on flavonol aglycones or 3-O- glycosylated anthocyanins (435 aa)    
Predicted Functional Partners:
F3H
Flavanone 3-hydroxylase; Catalyzes the 3-beta-hydroxylation of 2S-flavanones to 2R,3R-dihydroflavonols which are intermediates in the biosynthesis of flavonols, anthocyanidins, catechins and proanthocyanidins in plants (358 aa)
     
   
  0.927
FLS1
Flavonol synthase 1; Catalyzes the formation of flavonols from dihydroflavonols. It can act on dihydrokaempferol to produce kaempferol, on dihydroquercetin to produce quercitin and on dihydromyricetin to produce myricetin. In vitro catalyzes the oxidation of both enantiomers of naringenin to give both cis- and trans-dihydrokaempferol (336 aa)
     
   
  0.893
RHM1
Rhamnose biosynthesis 1; Trifunctional enzyme involved in UDP-beta-L-rhamnose biosynthesis, a precursor of the primary cell wall components rhamnogalacturonan I (RG-I) and rhamnogalacturonan II (RG-II) (PubMed-14671019, PubMed-17190829, PubMed-19056285). Plays a major role in supplying UDP-rhamnose for flavonol biosynthesis (PubMed-18757557). Catalyzes the dehydration of UDP-glucose to form UDP-4-dehydro-6-deoxy-D-glucose followed by the epimerization of the C3’ and C5’ positions of UDP-4-dehydro-6-deoxy-D-glucose to form UDP-4-keto-beta-L-rhamnose and the reduction of UDP-4-keto- beta [...] (669 aa)
     
   
  0.891
4CL3
4-coumarate-CoA ligase 3; Produces CoA thioesters of a variety of hydroxy- and methoxy-substituted cinnamic acids, which are used to synthesize several phenylpropanoid-derived compounds, including anthocyanins, flavonoids, isoflavonoids, coumarins, lignin, suberin and wall- bound phenolics (561 aa)
     
   
  0.793
UGT78D2
UDP-glucosyl transferase 78D2; Catalyzes the glycosylation of flavonoids from UDP- glucose. Catalyzes the glycosylation of anthocyanins from UDP- glucose. Possesses high quercetin 3-O-glucosyltransferase activity in vitro. Also active in vitro on benzoates and benzoate derivatives (460 aa)
     
   
0.725
TT4
Chalcone synthase; The primary product of this enzyme is 4,2’,4’,6’- tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin (395 aa)
     
   
  0.678
AT4G29440
Regulator of Vps4 activity protein (1090 aa)
           
  0.670
TT5
TRANSPARENT TESTA 5; Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2’,4’,6’-tetrahydroxychalcone (also termed chalcone) into naringenin (246 aa)
     
   
  0.646
DFR
Dihydroflavonol 4-reductase (382 aa)
         
  0.602
CHIL
Chalcone isomerase like; Involved in anthocyanin biosynthesis (209 aa)
     
   
  0.600
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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