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ASF1B ASF1B SWI3A SWI3A HDA15 HDA15 TOPII TOPII SDG16 SDG16 HAF01 HAF01 GTE4 GTE4 SDG29 SDG29 TAF7 TAF7 SDG14 SDG14 AT2G47210 AT2G47210
"GTE4" - Global transcription factor group E4 in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
GTE4Global transcription factor group E4; Involved in the activation and maintenance of cell division in the meristems and by this controls cell numbers in differentiated organs. Its action in cell cycle regulation may be directed through the RB-E2F pathway (766 aa)    
Predicted Functional Partners:
SDG29
SET domain group 29; Histone methyltransferase (1043 aa)
     
 
  0.898
AT2G47210
DNA methyltransferase 1-associated protein 1; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A (441 aa)
     
 
  0.896
HAF01
Transcription initiation factor TFIID subunit 1-A; TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription. Core scaffold of the TFIID complex (By similarity) (1919 aa)
     
  0.861
HDA15
Histone deacetylase 15; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity) (564 aa)
     
  0.841
TOPII
Topoisomerase II; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (1473 aa)
     
  0.825
SDG16
SET domain protein 16; Histone methyltransferase (1027 aa)
     
 
  0.823
SDG14
SET domain protein 14; Histone methyltransferase (1018 aa)
     
 
  0.822
SWI3A
SWI/SNF complex subunit SWI3A; Component of a multiprotein complex equivalent of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors (512 aa)
     
  0.808
TAF7
TBP-associated factor 7; TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription (239 aa)
     
 
  0.801
ASF1B
Histone chaperone ASF1B; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly (218 aa)
       
 
  0.799
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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