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G4 G4 SQS2 SQS2 PDS3 PDS3 PSY PSY ZDS ZDS CRTISO CRTISO Z-ISO Z-ISO LYC LYC LUT2 LUT2 ABA1 ABA1 AT3G47295 AT3G47295
"CRTISO" - Carotenoid isomerase in Arabidopsis thaliana
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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CRTISOCarotenoid isomerase; Carotene cis-trans-isomerase that converts 7,9,9’-tri- cis-neurosporene to 9’-cis-neurosporene and 7,9,9’,7’-tetra-cis- lycopene (also known as prolycopene) into all-trans-lycopene. Isomerization requires redox-active components, suggesting that isomerization is achieved by a reversible redox reaction acting at specific double bonds. Isomerizes adjacent cis-double bonds at C7 and C9 pairwise into the trans-configuration, but is incapable of isomerizing single cis-double bonds at C9 and C9’. Carotenoid biosynthesis is partly required to form the prolamellar bodies [...] (595 aa)    
Predicted Functional Partners:
ZDS
Zeta-carotene desaturase; Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7’. Shows stereoselectivity toward trans C15- C15’zeta-carotene double bond. The zeta-carotene produced by the phytoene desaturase PDS has a C15-C15’ double bond in the cis configuration and it requires isomerization before being recognized as substrate by ZDS. The main product is 7,9,7’,9’- tetra-cis-lycopene (pro-lycopene) (558 aa)
 
 
  0.999
LYC
Lycopene cyclase; Catalyzes the double cyclization reaction which converts lycopene to beta-carotene and neurosporene to beta-zeacarotene (501 aa)
         
  0.995
PSY
PHYTOENE SYNTHASE; Catalyzes the reaction from prephytoene diphosphate to phytoene (437 aa)
 
 
  0.995
LUT2
LUTEIN DEFICIENT 2; Catalyzes the single epsilon-cyclization reaction which converts lycopene to delta-carotene and neurosporene to alpha- zeacarotene. Required for lutein biosynthesis (524 aa)
     
 
  0.993
PDS3
Phytoene desaturase 3; This enzyme converts phytoene into zeta-carotene via the intermediary of phytofluene by the symmetrical introduction of two double bonds at the C-11 and C-11’ positions of phytoene. The zeta-carotene produced has a central C15-C15’ double bond in the cis configuration and it requires isomerization before being recognized as substrate by ZDS, the next enzyme in the lycopene biosynthesis pathway (566 aa)
 
 
  0.990
Z-ISO
15-cis-zeta-carotene isomerase; Isomerase involved in the biosynthesis of carotenoids. Catalyzes the cis- to trans-conversion of the 15-cis-bond in 9,15,9’-tri-cis-zeta-carotene (367 aa)
     
 
  0.978
AT3G47295
Tyrosine-sulfated glycopeptide 2; Promotes cellular proliferation and expansion (71 aa)
           
  0.865
ABA1
ABA DEFICIENT 1; Zeaxanthin epoxidase that plays an important role in the xanthophyll cycle and abscisic acid (ABA) biosynthesis. Converts zeaxanthin into antheraxanthin and subsequently violaxanthin. Required for resistance to osmotic and drought stresses, ABA- dependent stomatal closure, seed development and dormancy, modulation of defense gene expression and disease resistance and non-photochemical quencing (NPQ). Through its role in ABA biosynthesis, regulates the expression of stress-responsive genes such as RD29A during osmotic stress and is required for normal plant growth durin [...] (667 aa)
           
  0.819
G4
Chlorophyll synthase; Involved in one of the last steps of the biosynthesis of chlorophyll a. Catalyzes the esterification of chlorophillide a or b with a preference for geranylgeranyldiphosphate (GGPP) rather than for phytyldiphosphate (PhyPP) (387 aa)
 
   
  0.817
SQS2
Squalene synthase 2 (413 aa)
   
 
  0.811
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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