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AT3G57620 AT3G57620 CYCD4;1 CYCD4;1 AT1G08180 AT1G08180 UVI4 UVI4 IMPA-2 IMPA-2 SIM SIM CDKB1;1 CDKB1;1 CDC2 CDC2 AT5G02420 AT5G02420 LGO LGO CYCD2;1 CYCD2;1
"AT1G08180" - Uncharacterized protein in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
AT1G08180Uncharacterized protein; Probable cyclin-dependent protein kinase (CDK) inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle (111 aa)    
Predicted Functional Partners:
AT3G57620
Glyoxal oxidase-related protein (547 aa)
           
  0.879
AT5G02420
Uncharacterized protein; Probable cyclin-dependent protein kinase (CDK) inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle (115 aa)
           
  0.863
LGO
LOSS OF GIANT CELLS FROM ORGANS; Probable cyclin-dependent protein kinase (CDK) inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle. Specifically regulates endoreduplication in epidermal pavement cells to produce the cell size pattern. Is necessary for giant cell formation (128 aa)
           
  0.848
CDKB1;1
Cyclin-dependent kinase B1-1; May control G2/M (mitosis) phase progression. Plays a role in regulating seedling growth in darkness via regulation of hypocotyl cell elongation and cotyledon cell development. Plays a role in stomatal development. Required to suppress endoreduplication (309 aa)
       
 
  0.812
CYCD2;1
Cyclin D2;1; Acts on the G1 phase of the cell cycle to control cell division rate in both shoot and root meristems. The complex formed with CDKA-1 phosphorylates plant retinoblastoma protein (362 aa)
       
 
  0.722
SIM
SIAMESE; Probable cyclin-dependent protein kinase (CDK) inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle. Required for normal trichome endoreplicating cell cycles (127 aa)
           
  0.671
IMPA-2
Importin alpha isoform 2; Binds to conventional NLS motifs and mediates nuclear protein import across the nuclear envelope (By similarity). Acts as cellular receptor for the nuclear import of the virD2 protein of Agrobacterium, but is not essential for Agrobacterium-mediated root transformation (PubMed-18836040) (535 aa)
       
 
  0.633
CYCD4;1
CYCLIN D4;1; May activate cell cycle in the root apical meristem (RAM) and promote embryonic root (radicle) protrusion (318 aa)
           
  0.552
UVI4
UV-B-INSENSITIVE 4; Negative regulator of the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase required for proper mitotic progression and cell fate determination; inhibits premature cell differentiation. Prevents DNA endoreplication by promoting the maintenance of the mitotic state by preferentially inhibiting APC/C(FZR) and triggering cyclins accumulation (e.g. CYCB1-1, CYCB1-2 and CYCA2-3) in a temporal manner. Required for megagametophyte and endosperm development. Counteracts the activity of CCS52A1 thus inhibiting the turnover of CYCA2-3. Confers immunity to bacteria [...] (259 aa)
           
  0.509
CDC2
Cell division control 2; Involved in the control of the cell cycle. Essential for both G1/S and G2/M (mitosis) phase transitions. Functions in cell morphogenesis as well as cell proliferation. Required for cell division (entry into mitosis) of the generative cell in male gametogenesis (294 aa)
           
  0.478
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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